Table 7 Association of studied SNPs with gender and severity

Males

rs2285666

C

19

73.1%

89

74.2%

-

1

Reference

T

7

26.9%

31

25.8%

0.909

0.969

0.565–1.662

rs12329760

CC

20

76.92%

74

61.67%

-

1

Reference

CT

6

23.08%

26

21.67%

0.759

1.094

0.614–1.950

TT

0

0%

20

16.67%

1

-

-

C

46

88.5%

174

72.5%

-

1

Reference

T

6

11.5%

66

27.5%

0.014

1.774

1.124–2.801

Females

rs2285666

CC

42

64.62%

57

53.77%

-

1

Reference

CT

13

20.00%

25

23.58%

0.379

1.241

0.768–2.005

TT

10

15.38%

24

22.64%

0.178

1.420

0.853–2.362

C

97

74.6%

139

65.6%

-

1

Reference

T

33

25.4%

73

34.4%

0.078

1.306

0.971–1.758

rs12329760

CC

39

60.00%

98

92.45%

-

1

Reference

CT

13

20.00%

4

3.77%

< 0.001

0.275

0.138–0.550

TT

13

20.00%

4

3.77%

< 0.001

0.275

0.138–0.550

C

91

70.0%

200

94.3%

-

1

Reference

T

39

30.0%

12

5.7%

< 0.001

0.298

0.198–0.448