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Table 1 Clinical profiles of 272 patients with Hepatitis B infection

From: Correlation analysis of hepatic steatosis and hepatitis B virus: a cross-sectional study

Variables

CHB (n = 128)

CHB + MAFLD (n = 144)

Total (n = 272)

P value

Male, n (%)

64 (50.0)

92 (63.9)

156 (57.4)

0.021*

Age (years)

47 (36–54)

44 (38–53)

44 (37–53)

0.898

Family history of HBV, n (%)

65 (50.8)

73 (50.7)

138 (50.7)

0.989

Diabetes, n (%)

8 (6.3)

23 (16.0)

31 (11.4)

0.012*

Cirrhosis, n (%)

10 (7.8)

24 (16.7)

34 (12.5)

0.028*

Hepatocellular carcinoma, n (%)

7 (5.5)

7 (4.9)

14 (5.1)

0.821

BMI (kg/m2)

23.9 (22.1–25.3)

25.1 (24.2–26.5)

24.6 (23.1–26.0)

 < 0.001*

Overweight/obesitya, n (%)

54 (42.2)

113 (78.5)

167 (61.4)

 < 0.001*

Waist-to-hip ratio

0.88 (0.83–0.92)

0.89 (0.84–0.96)

0.89 (0.83–0.95)

0.142

CAP values (dB/m)

209 (186–227)

273 (259–295)

250 (214–274)

 < 0.001*

LSM values (kPa)

5.5 (4.5–7.8)

6.7 (5.1–8.5)

6.2 (4.6–8.1)

0.233

ALT (U/L)

28.0 (19.3–37.0)

29.0 (21.3–43.0)

29.0 (21.0–39.0)

0.708

Elevated ALTb, n (%)

22 (17.2)

41 (28.5)

63 (23.2)

0.028*

  1. Data are expressed as median (IQR) or number (%)
  2. *Statistically significant at P < 0.05
  3. BMI Body mass index, CAP Controlled attenuation parameter, LSM Liver stiffness measurement, ALT Alanine aminotransferase
  4. aThe study included Chinese participants, with overweight/obesity defined as BMI ≥ 24 kg/m2
  5. bElevated ALT was considered when exceeding the local upper limit of normal (ULN), with ALT > 40 U/L