Table 1 Log differences in the CHIKV titre compared to virus control on treatment with individual and combination of drugs under post treatment conditions

1

2-FA

100

1.184

2-FA + Emetine

2-FA + Enalprilat

2-FA + Lomibuvir

2-FA + Metyrapone

2-FA + Resveratrol

100 + 200

100 + 1.56

100 + 6.25

100 + 200

100 + 12.5

2.10

2.11

1.00

2.04

1.89

2

Emetine

200

1.215

Emetine + Enalprilat

Emetine + Lomibuvir

Ementine + Metyrapone

Emetine + Resveratrol

100 + 1.56

100 + 6.25

100 + 200

100 + 12.5

1.14

0.72

1.14

0.24

3

Enalprilat

100

1.08

Enalprilat + Lomibuvir

Enalprilat + Metyrapone

Enalprilat + Resveratrol

1.56 + 6.25

1.56 + 200

1.56 + 100

1.19

1.07

0.26

4

Lomibuvir

6.25

1.215

Lomibuvir + Metyrapone

Lomibuvir + Resveratrol

6.25 + 200

6.25 + 12.5

0.93

0.94

5

Metyrapone

100

1.203

Metyrapone + Resveratrol

200 + 12.5

1.1204

6

Resveratrol

12.5

1.01