The rates and symptoms of natural and breakthrough infection pre- and post- Covid-19 non-mRNA vaccination at various peaks amongst Iranian healthcare workers

Table 1 Pattern and frequency of SARS-CoV-2 infection in natural, natural/ breakthrough, and breakthrough infected healthcare workers, Shiraz, Iran. Minus and plus signs indicate infection pre- and post-receiving of the full dose of vaccination, respectively (N = 5612)

Number of SARS-CoV-2 positive test	Natural infected HCWs - [N = 2195(%)]	Natural/ Breakthrough infected HCWs -/+ [N = 632(%)]	Breakthrough infected HCWs + [N = 2785(%)]
1	-1 [N = 2056(93.7%)]	……	+ 1 [N = 2498(89.7%)]
2	-2 [N = 129(5.9%)]	-1/+1[ N = 552 (87.3%)]	+ 2 [N = 279 (10%)]
3	-3[ N = 10(0.4%)]	-2/+1 [N = 38 (6%)] -1/+2 [N = 31 (4.9%)]	+ 3 [N = 7(0.27%)]
4	……	-2/+2[ N = 4 (0.6%)] -3/+1[ N = 6(1%)]	+ 4 [N = 1(0.03%)]
5	……	-2/+3 [N = 1(0.2%)]	……

Abbreviation: HCW = healthcare worker
Data are presented as case number (percentages)
HCWs who were naturally infected were denoted with a negative sign, and the number next to it indicated the number of infections; similarly, those who had a natural/breakthrough SARS-CoV-2 infection were denoted with a -/+ sign, and the number next to it indicated the number of infections SARS-CoV-2 before/after vaccination; and finally, those who had the breakthrough form are denoted with a positive sign, which denotes the number of times the person contracted the infection after receiving the vaccine

ISSN: 1743-422X