TLR2 2258 G>A single nucleotide polymorphism and the risk of congenital infection with human cytomegalovirus

Table 5 Distribution of the alleles, located in TLR2 2258 G>A polymorphic site

A.
Gene polymorphism and allele	No.^a of carriers with TLR2 alleles (%)		P-value
	Infected cases	Controls
TLR2 2258 G>A
G	35 (87.5)	61 (98.4)	0.033^b
A	5 (12.5)	1 (1.6)
B.
Gene polymorphism and allele	No.^a of carriers with TLR2 alleles (%)		P-value
	Symptomatic cases	Asymptomatic cases
TLR2 2258 G>A
G	20 (90.9)	15 (83.3)	0.471^c
A	2 (9.1)	3 (16.7)

The prevalence rates of alleles in TLR2 SNP were compared between infected and uninfected fetuses and newborns (A) as well as between symptomatic and asymptomatic offsprings with congenital cytomegaly (B)
P ≤ 0.050 is considered significant
^a No. number
^bFisher’s exact test
^cPearson’s Chi-squared test

ISSN: 1743-422X