Table 1 Main gross and histological findings observed in EMCV outbreak
Species | N° of animals | Gross pathology(a) | Histological findings(a) |
|---|---|---|---|
Macaca sylvanus | 4 | Sero-haemorrhagic pleural and pericardial fluid (4), pulmonary oedema and congestion (4), liver congestion (4), kidney congestion (3), meningeal congestion (3) | Severe lymphocytic and neutrophilic interstitial myocarditis, with areas of necrosis (4/4), congested organs (4/4) |
Hystrix cristata | 17 | Sero-haemorrhagic pleural and pericardial fluid (11), sero-haemorrhagic peritoneal fluid (6), pulmonary oedema and congestion (10), cardiomegaly and grey-white necrotic foci in the myocardium (5), meningeal congestion (2) | (b)Severe lymphocytic and neutrophilic interstitial myocarditis, with areas of necrosis (9), multifocal lymphocytic meningoencephalitis (6), pulmonary congestion (9) |