Fig. 2From: Rift Valley fever virus NSs protein functions and the similarity to other bunyavirus NSs proteinsSchematics of RVFV NSs-mediated TFIIH suppression. The top portion of the figure illustrates that RVFV NSs protein binds to p44, and sequesters it from the assembly site of TFIIH. Whereas the bottom portion of the figure illustrates the formation of the E3 ligase complex, consisting of cullin 1 (CUL1), Skp1, and FBXO3, and promoting the subsequent degradation of p62 through RVFV NSsBack to article page