Fig. 4
From: Biological function of Foot-and-mouth disease virus non-structural proteins and non-coding elements
Known functions of FMDV nonstructural proteins on cellular regulation. Purple circles: FMDV nonstructural proteins. Red arrow: activation of downstream gene expression. Orange line with vertical stub: inhibition of downstream proteins. kB, a canonical kB element response to Nuclear factor kB (NF-kB). ISRE, IFN-sensitive response element. Caspases, represent a class of genes inducing apoptosis and inflammation