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Fig. 3 | Virology Journal

Fig. 3

From: Pre-immune state induced by chicken interferon gamma inhibits the replication of H1N1 human and H9N2 avian influenza viruses in chicken embryo fibroblasts

Fig. 3

Viral gene replication in CEF expressing chIFN-γ and suppressed by siRNA targeting chIFN-γ. CEFs were harvested and analyzed by real-time RT-PCR after H1N1 and H9N2 virus infection. a The mRNAs of viral glycoprotein (HA) and viral polymerase (PB2) were significantly reduced in pcDNA-chIFN-γ-transfected CEFs compared to the control. b HA and PB2 mRNA was significantly increased in siRNA targeting chIFN-γ transfected CEFs compared to the control. Statistical significance was determined by unpaired student t-test (*P < 0.05, **P < 0.01, and ***P < 0.001)

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Virology Journal

ISSN: 1743-422X