Figure 1
From: Biological characteristics of the rtA181T/sW172* mutant strain of Hepatitis B virus in animal model
Time-dependent HBV antigen and HBV DNA expression in mice serum after hydrodynamic transfection in vivo. Mice were injected with 10μg pHBV4.1 (Wt) or pHBV rtA181T/sW172* (Mut) respectively. At different time points, HBsAg (A) and HBeAg (B) in the serum were measured by ELISA, and HBV DNA (C) in the serum were detected by quantitative real-time PCR. The mean HBsAg, HBeAg and DNA levels plus standard deviation (indicated by error bars) from three independent analyses are shown (* P<0.001).