Skip to main content

Table 2 Immunization schedule

From: Sublingual immunization with recombinant adenovirus encoding SARS-CoV spike protein induces systemic and mucosal immunity without redirection of the virus to the brain

Group

1st (day 0)

2nd (day 14)

3rd (day 28)

Routesa

1

rADV-Mock

rADV-Mock

rADV-Mock

i.m.

2

rADV-S 2 × 107

rADV-S 2 × 107

rADV-S 2 × 107

i.m.

3

rADV-S 2 × 107

rADV-S 2 × 107

rADV-S 2 × 107

i.n.

4

rADV-S 1 × 108

rADV-S 1 × 108

rADV-S 1 × 108

i.n.

5

rADV-S 2 × 107

rADV-S 2 × 107

rADV-S 2 × 107

s.l.

6

rADV-S 1 × 108

rADV-S 1 × 108

rADV-S 1 × 108

s.l.

  1. a Groups of six BALB/c mice were immunized s.l., i.n., or i.m. with rADV-S three times at 2-week intervals.
Back to article page

Virology Journal

ISSN: 1743-422X