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Figure 1 | Virology Journal

Figure 1

From: Avian influenza virus H5N1 induces rapid interferon-beta production but shows more potent inhibition to retinoic acid-inducible gene I expression than H1N1 in vitro

Figure 1

Infection of avian influenza virus H5N1 resulted in robust NP gene expression and rapid IFN-β production. A549 cells were infected with influenza viruses(m.o.i = 2). At the indicated time point, cells were collected and performed to extract total RNA. Quantitative RT-PCR was used to detect the copy numbers of the influenza virus NP gene, human IFN-β gene in A549 cells, and normalized with human β-actin gene copy numbers. Data are shown as mean ± SD of three independent experiments. ( A) The expression pattern of NP gene in A549 cells. ( B) The induction of IFN-β gene in A549 cells. Significance was determined using two-tailed Student’s t test (*, P < 0.05).

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Virology Journal

ISSN: 1743-422X