Table 3 HCV negative strand RNA detection by rTth RT-PCR in chronic HCV-infected individuals

Cadavers

0/6 S, 1/4 lymph; 3/6 CNS

10 CNS to 100 S

[84]

Co-infected, cadavers

7/8 L, 5/8 lymph, 5/8 pancreas, 2/8 adrenal & thyroid, 1/8 BM & spleen

10-100 Various

[29]

Co-infected

15/20 PBMC

[45]

Co-infected

0/10 S, 6/10 PBMC, 4/10 M, 2/10 CD4+ & CD8+ T cells, 1/10 CD19+ B, 2/6 M cultured

10-100 Various

[70]

Co-infected women

13/47 S, 17/48 PBMC

[104]

Co-infected women

61/144 PBMC; 78/315 total specimens

[182]

HCV recovered

9 of 12 PBMC (mitogen stimulated in vitro)

[32]

Humans, Chimps

2/2 S, 0/10 PBMC

10 L; >= 1000 S

[183]

Ischemic heart disease

8/10 Carotid plaque

[184]

Lichen planus

3/3 Skin

[185]

Lichen planus/MC+Cutaneous Vasculitis

0/19 Skin

[186]

LT

42/44, as soon as 7 days post-LT

[94]

LT

0/9 PBMC before transplantation and 3/9 PBMC after

[97]

Lymphoproliferative

4/16 B

[187]

Mixed cryoglobulinemia

6/46 PBMC, 5/46 BM

[188]

Occult

10/10 L, 5/6 PBMC

1-40 L, 1-2 PBMC

[189]

Occult

56/62 L of HCV+ positive, 27/44 L of HCV+ negative

[33]

Occult

11/18 PBMC

10-100 PBMC

[36]

SVR

15/19 L; 12/13 PBMC

6 PBMC, 2.6 L

[57]

Chronic

5/30 in B, 2/30 non-B cells

[190]

Chronic

4 of 17 Oral

[191]

Chronic

6/6 L, 0/6 S

10-100 L

[89]

Chronic

3/3 L

100-1000 L

[192]

Chronic

0/47 Leukocyte, 3/3 Liver

41 L

[193]

Chronic

2/2 L, HCV-strand declines in concentration with increasing time before storage

[194]

Chronic

57/61 L

10-1000 L

[195]

Chronic

5'UTR, Heat 60 min, RNase: 7/9 PBMC, 0/9 S; rTth: 2/3 L, 0/4 S, 0/4 PBMC

[196]

Chronic

4/4 liver, 4/8 PBMC

[197]

Chronic

0/33 P, 0/33 PBMC

[67]

Chronic

39/48 L

10 L

[198]