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Table 3 Replication and transmission study of recombinant virus 2H7N2:6WF10att and 2mH7N2:6WF10att in quail

From: Improved hatchability and efficient protection after in ovo vaccination with live-attenuated H7N2 and H9N2 avian influenza viruses

Virus

Group

# of positive tracheal swab/total # post-inoculation (log10TCID50/ml ± SD) at peak viral shedding

# of seroconverted/total # (Average HI titer at 14 dpi)

  

1 dpi

3 dpi

5dpi

7 dpi

9 dpi

 

2H7N2:6WF10att

Inoculated

6/6 (2.9 ± 0.4)

6/6*

3/3

0/3

0/3

3/3 (133)

 

Contact

NA

3/3 (1.6 ± 1.4)

3/3

2/3

0/3

3/3 (47)

2mH7N2:6WF10att

Inoculated

6/6 (<0.7)

6/6*

1/3

1/3

0/3

3/3 (87)

 

Contact

NA

0/3

0/3

2/3 (<0.7)

0/3

2/3 (10)

  1. * 3 quail from each inoculated group were sacrificed at 3 dpi to determine virus load in the lungs.