Table 2 Frequencies of IL-10 Promoter Alleles and Genotype/Haplotypes in Patients With HBV and healthy Control Population
patients (%) | control (%) | OR | P | |
|---|---|---|---|---|
Allele | n = 52 × 2 | n = 48 × 2 | ||
- 1082G | 4(3.9) | 3(3.1) | 1.24 | 0.99 |
- 1082A | 100(98) | 93(96.8) | 0.81 | 0.99 |
- 819C | 18(17.3) | 18(18.7) | 0.91 | 0.85 |
- 819T | 86(92.7) | 78(81.3) | 1.97 | 0.85 |
38(36.5) | 22(22.9) | 1.88 | 0.05 | |
- 592A | 66(63.4) | 74(77.1) | 0.52 | 0.05 |
Genotype | n = 52 | n = 48 | ||
- 592 A/A | 23 (44.2) | 30 (62.5) | 0.48 | 0.08 |
A/C | 20(38.4) | 14(29.2) | 1.52 | 0.40 |
C/C | 9(17.3) | 4(8.3) | 2.3 | 0.24 |
- 819T/T | 36(69.2) | 33(68.8) | 1.02 | 0.99 |
T/C | 12(23.1) | 12(23.1) | 0.9 | 0.99 |
C/C | 4(7.7) | 4(7.7) | 1.25 | 0.99 |
- 1082 A/A | 48(92.3) | 45(93.8) | 0.8 | 0.99 |
A/G | 4(7.7) | 3(6.3) | 1.25 | 0.99 |
G/G | 0(0) | 0(0) | ||
Heplotype(-1082/-819/-592) | ||||
n = 52 | n = 48 | |||
GCC | 4 (7.6) | 3(6.2) | 1.25 | 0.99 |
ACC | 13 (25) | 14(29.1) | 0.81 | 0.66 |
ATA | 41 (78.8) | 43(89.5) | 0.43 | 0.18 |
GTA | 2 (3.8) | 2(4.1) | 0.92 | 0.99 |