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Table 2 The neutralization titers of serum and protective immunity in vaccinated mice

From: Mutation of putative N-Linked Glycosylation Sites in Japanese encephalitis Virus Premembrane and Envelope proteins enhances humoral immunity in BALB/C mice after DNA vaccination

DNA Vaccine

PRNT50

Survival rate (%)

pVAX-prME-WT

13 ± 4

90b

pVAX-prME-M1

15 ± 5

90b

pVAX-prME-M2

35 ± 9a

100b

pVAX-prME-M3

38 ± 8a

100b

pVAX-(Control)

< 5

10

  1. Data are shown as mean ± standard error (S.E.). Statistical analysis was performed using Student's t-test.
  2. a Significance (P < 0.05 to 13 ± 4 and 15 ± 5).
  3. b Significance (P < 0.05 to 10%).