Figure 5From: Influenza A virus NS1 gene mutations F103L and M106I increase replication and virulenceVirulence and body weight loss are increased by 103L and 106I NS1 mutations in rPR8- H5N1-NS. A. Groups of 3 BALB/c mice were infected intranasally with 104 pfu with the different rPR8 viruses. Survival was monitored for 9 dpi. B. The percent of body weight loss was calculated relative to body weights that were recorded daily throughout the whole course of the experiment.Back to article page