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Figure 2 | Virology Journal

Figure 2

From: Role of cellular caspases, nuclear factor-kappa B and interferon regulatory factors in Bluetongue virus infection and cell fate

Figure 2

Cleavage of caspase-3 by BTV-1 infection either in inhibitor-treated cells or in knock-out cells. A: Immunoblot of Caspase-3 using anti-caspase-3 polyclonal antibody (Abcam: ab17819). B: The cleavage of caspase-8 in caspase-9 inhibitor (z-LEHD-FMK) treated cells infected with BTV-1. The 18 kDa cleaved product and a 26 kDa non-specific band (*) are indicated. C: Immunoblot of capase-3 cleavage products at different times of BTV-1 infection in caspase-9 deficient Jurkat T-cells (JurkatΔC9) and complemented caspase-9 deficient Jurkat T-cells (Jurkat compΔC9) using an alternate anti-caspase-3 polyclonal antibody (Abcam: ab90437). Representative results from three independent experiments are shown.

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Virology Journal

ISSN: 1743-422X