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Figure 1 | Virology Journal

Figure 1

From: Impaired antiviral activity of interferon alpha against hepatitis C virus 2a in Huh-7 cells with a defective Jak-Stat pathway

Figure 1

Structure of HCV full-length and sub-genomic clones used in this project. The coding sequence of GFP was inserted in frame with the NS5A coding sequence of JFH1 cDNA clone between 2394 and 2395 amino acids position (between 417 and 418 amino acids of NS5A protein). Changes in the nucleotide and amino acid sequences of NS5A gene of HCV-GFP chimera clone are shown. GFP was also inserted at the similar location of NS5A gene (between 417 and 418 amino acids) in the sub-genomic clone, GND mutant clone and E1-E2 deleted mutant clone.

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Virology Journal

ISSN: 1743-422X