Table 1 Description of included randomized controlled trials

Study	Study design	Grade	Treatment options	Study location	dosage of drugs		Treatment
					LAM	LdT
Lai 2005[6]	RCT, DB	5	LAM vs LdT	Global	100 mg	400/600 mg	12 months
Lai 2007[7]	RCT, DB	5	LAM vs LdT	Global	100 mg	600 mg	12 months
Rasenack 2007[17]	RCT, DB	4	LAM vs LdT	Global	100 mg	600 mg	24 months
Jia 2007[16]	RCT, DB	4	LAM vs LdT	China	100 mg	600 mg	24 months
Hou 2008[10]	RCT, DB	4	LAM vs LdT	China	100 mg	600 mg	12 months
Liaw 2009[15]	RCT, DB	5	LAM vs LdT	Global	100 mg	600 mg	24 months
Cai 2009[13]	RCT, DB	5	LAM vs LdT	China	100 mg	600 mg	12 months
Yang 2009[14]	RCT	3	LAM vs LdT	China	100 mg	600 mg	12 months
Zhong 2009[11]	RCT	3	LAM vs LdT	China	100 mg	600 mg	12 months
Chen 2009[9]	N/A	2	LAM vs LdT	China	100 mg	600 mg	12 months
Tang 2009[8]	RCT	3	LAM vs LdT	China	100 mg	600 mg	12 months

RCT, randomized controlled trial; DB, double blind; LAM, Lamivudine; LdT, Telbivudine

ISSN: 1743-422X