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Table 2 Characteristics of six patients whose dental problems delayed the initiation of IFN therapy

From: Dental problems delaying the initiation of interferon therapy for HCV-infected patients

No.

Age

Sex

Liver Disease

HCV RNA

HCV genotype

Dental problems that delayed the initiation of Peg-IFN therapy

Period to onset of IFN treatment after dental therapy (days)

Underlying disease

IFN therapy

Effect of IFN treatment

1

50

F

CH-C

980 kIU/ml

1b

#1. Acute periostitis of the right maxilla, #2. Periapical periodontitis of the right maxillary first molar

49

Gallbladder polyp

Peg-IFN alfa-2b/RBA

TR

2

67

M

CH-C

3,940 kIU/ml

1b

#1. Acute alveolar abscess of bilateral mandibular molars, #2. Periodontal diseases of the right mandibular first and second molars, the left mandibular first molar, and the left maxilla first and second molars

105

Gastric ulcer

Peg-IFN alfa-2b/RBA

NR

3

36

M

CH-C

over 500 kIU/ml

1b

Periapical periodontitis of the right mandibular second molar

4

None

Peg-IFN alfa-2b/RBA

SVR

4

47

F

CH-C

43 kIU/ml

2a

#1. Pulpitis of the right maxillary first premolar, the left maxillary second premolar, and the right mandibular second premolar, #2. Tooth stumps of the left maxillary canine and second premolar, and the right mandibular first premolar, #3. Dental caries of the right maxillary lateral incisor

97

Hypertension, Adjustment disorder, Gallstone

Peg-IFN alfa-2a

SVR

5

59

F

LC-C

471 kIU/ml

2a

#1. Periapical periodontitis and gingival abscess of the right mandibular lateral incisor, #2. Dental caries of bilateral mandibular central incisors

105

Depression, Hypertension, Osteoarthritis of the spine, Esophageal varices

Peg-IFN alfa-2b/RBA

SVR

6

25

F

CH-C

6.2 logIU/mL

1b

#1. Pericoronitis of the right mandibular wisdom tooth, #2. Horizontal impacted wisdom teeth of bilateral mandibles

8

None

Peg-IFN alfa-2b/RBA

SVR

  1. CH-C: chronic hepatitis C, LC-C: liver cirrhosis, Peg-IFN: pegylated interferon, RBV: ribavirin,
  2. TR: transient biochemical responders, NR: nonresponder, SVR: sustained virological response