Ethnic and geographical differences in HLA associations with the outcome of hepatitis C virus infection

Table 2 HLA-class I allele frequencies of HCV infected subjects

Allele	Chronic(%) 2n = 112	Clearance (%) 2n = 98	Odds Ratio	95% CI	p-value
A*01	15.2	9.18	2.05	0.79–5.32	0.14
A*02	26.8	26.0	1.04	0.48–2.24	0.92
Caucasian	30.3	17.4	2.07	0.82–5.21	0.12
non-Cauc	21.7	32.7	0.57	0.23–1.42	0.23
A03	9.82	16.7	0.54	0.24–1.20	0.14
A*11	3.57	6.25	0.55	0.15–2.08	0.38
A*23	1.79	4.17	0.42	0.07–2.38	0.33
A*24	10.7	15.0	0.94	0.37–2.38	0.90
A*25	1.79	1.25	1.78	0.16–20.2	0.64
A*29	5.34	1.25	0.18	0.02–1.50	0.12
A*30	7.14	3.12	2.56	0.64–10.2	0.19
A*31	3.57	5.21	0.68	0.17–2.68	0.58
A*32	1.79	4.17	0.42	0.07–2.38	0.33
A*33	2.68	1.04	2.71	0.27–27.0	0.39
A*68	2.68	4.17	0.64	0.14–2.08	2.99
A*74	2.68	1.04	0.37	0.04–3.66	0.62
Cw*01	1.79	4.08	0.57	0.09–3.55	0.55
Cw*02	9.84	7.16	1.47	0.52–4.13	0.47
Cw*03	10.7	9.18	1.21	0.46–3.18	0.70
Cw*04	16.9	13.2	1.31	0.56–3.06	0.53
Cw*05	0.89	7.16	0.12	0.01–0.97	0.03
Cw*06	8.94	9.18	1.11	0.40–3.09	0.84
Cw*07	28.6	28.6	0.88	0.41–1.91	0.75
Cw*08	4.46	3.06	1.18	0.25–5.55	0.84
Cw*12	3.58	6.12	0.55	0.15–2.08	0.38
Cw*15	3.58	2.05	1.81	0.32–10.3	0.51
Cw*16	7.15	8.16	0.85	0.29–2.48	0.77

*: A*03 is protective for non-Caucasians, OR = 0.20, 95% CI = 0.04–1.01, P = 0.04
Note: Only those alleles except Cw*05 with more than 1.0% frequency in both comparison groups are shown.
Non-Cauc: non-Caucasians.

ISSN: 1743-422X