Figure 2
From: Inhibition of Monkeypox virus replication by RNA interference
Identifying the most potent antiviral siRNA construct within siA6 and siE8 pools. MK2 cells transfected with 40 nM of one of the four constructs multiplexed in siA6 or siE8 pools, i.e., siA6R-a, -b, -c, -d or siE8L-a, -b, -c, -d. Transfected cells were infected with MPV and viral replication was determined at 48 h PI using plaque assay. Results are presented as a percentage of average plaque counts in treated cells to that in mock transfected control cells. siA6-a and siE8-d showed the strongest antiviral effect.