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Table 2 Metastatic nodes in lungs

From: Herpes simplex virus type-1(HSV-1) oncolytic and highly fusogenic mutants carrying the NV1020 genomic deletion effectively inhibit primary and metastatic tumors in mice

Experimental groups

No. of mice in group

No. of metastatic nodes in lungs of experimental animalsa

  

mouse1

mouse2

mouse3

mouse4

mouse5

mouse6

mouse7

mouse8

PBS

7

3

5

3

18

3

10

1

 

OncdSyn

8

2

0

0

0

2

0

0

0

  1. Experimental animals in PBS and OncdSyn groups were sacrificed on day 33 post-inoculation of 4T1 cells and the lungs were removed and examined for metastatic node formation as described in Materials and Methods. aPBS > OncdSyn (Wilcoxon Two-Sample test, p = 0.002).
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Virology Journal

ISSN: 1743-422X