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Table 1 Sequence polymorphisms in the HPV-33 E6 variants

From: Comparison of p53 and the PDZ domain containing protein MAGI-3 regulation by the E6 protein from high-risk human papillomaviruses

Codon Position

HPV-33 E6 Variants

Nucleotide Change

Amino Acid Change

18

5

C to T

A to V

28

8

T to G

L to R

36

6, 7, 8

A to C

K to N

36

3, 5

C to A

P to T

69

2, 3, 5

C to T

F to F (none)

73

2, 3, 5

A to C

I to L

83

2, 3, 5

G to T

V to L

86

7

A to C

N to H

93

2, 3, 5

A to C

K to N

125

7

A to T

R to R (none)

138

2, 3, 5

C to T

A to V

142

2, 3, 5

C to T

S to S (none)

  1. Codon positions of polymorphisms pertaining to the HPV-33 E6 variants. Also indicated are the specific changes in nucleotide and amino acid sequence from that of the HPV-33 E6 prototype (i.e. prototype nucleotide/amino acid to polymorphic nucleotide/amino acid).