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Figure 6 | Virology Journal

Figure 6

From: Comparison of p53 and the PDZ domain containing protein MAGI-3 regulation by the E6 protein from high-risk human papillomaviruses

Figure 6

Comparison of E6-mediated ubiquitination of p53 and MAGI-3. Panel A. p53 ubiquitination in nuclear and cytoplasmic extracts from cells transfected with plasmids expressing pcDNA3 (control), MDM2 and HPV-16 E6 as indicated. Panel B. MAGI-3 ubiquitination from cells transfected with plasmids expressing pcDNA3 (control), HPV-16 E6, HA-tagged ubiquitin (Ub) alone, or HPV-16 E6 + HA-tagged ubiquitin (Ub). Panel C. MAGI-3 protein levels in cells transfected with plasmids expressing pcDNA3 (control), HPV-16 E6, HA-tagged ubiquitin (Ub) alone, or HPV-16 E6 + HA-tagged ubiquitin (Ub).

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Virology Journal

ISSN: 1743-422X