Skip to main content
Figure 1 | Virology Journal

Figure 1

From: Vaccinia virus lacking the deoxyuridine triphosphatase gene (F2L) replicates well in vitro and in vivo, but is hypersensitive to the antiviral drug (N)-methanocarbathymidine

Figure 1

Genomic structure of the F2L region of VV Δ F2L-gfp. The F2L gene in VV strain WR (shaded arrow in the top line) was replaced with the gfp gene driven by the synthetic E/L promoter (black arrow in the bottom line). The resulting virus was designated VV Δ F2L-gfp and contained a deletion in F2L corresponding to amino acids 11–129 of the open reading frame.

Back to article page

Virology Journal

ISSN: 1743-422X