Figure 1From: Nectin-2-mediated entry of a syncytial strain of herpes simplex virus via pH-independent fusion with the plasma membrane of Chinese hamster ovary cellsSyncytium formation of HSV-1 strain ANG path on CHO cells expressing nectin-1 or nectin-2. HSV-1 ANG path was added to wild type CHO (A), CHO-nectin-1 (B) or CHO-nectin-2 cells (C) for 24 h. Based on the titration of ANG path on Vero cells, the MOIs were 1000 (A), 100 (B), or 1 (C). Visualization of syncytia was facilitated by immunoperoxidase staining with HR50 antibody to HSV. Magnification, 4×.Back to article page