Strategically examining the full-genome of dengue virus type 3 in clinical isolates reveals its mutation spectra

Table 3 Mean p-distance and ratio of dN to dS per site of amino acid among different domains of the E protein in DENV-3 infected patients

Virus ID	No of sequences	Envelope (293aa)		Domain I (70aa)		Domain II (106aa)		Domain III (100aa)
		Mean p-distance	dN/dS	Mean p-distance	dN/dS	Mean p-distance	dN/dS	Mean p-distance	dN/dS
1F	26	0.006 ± 0.001	2.04	0.009 ± 0.003	1.82	0.005 ± 0.002	1.72	0.005 ± 0.002	2.8
1H	21	0.008 ± 0.002	1.11	0.008 ± 0.004	2.53	0.007 ± 0.003	0.59	0.007 ± 0.002	1.2
2F	18	0.007 ± 0.002	1.38	0.009 ± 0.004	2.52	0.006 ± 0.003	1.04	0.007 ± 0.003	2.57
2H	25	0.012 ± 0.002	1.06	0.013 ± 0.004	2.68	0.012 ± 0.004	1.08	0.011 ± 0.003	0.77
3F	23	0.007 ± 0.001	0.81	0.012 ± 0.004	0.96	0.005 ± 0.002	0.45	0.003 ± 0.002	1.76
3H	23	0.009 ± 0.002	1.46	0.014 ± 0.005	4.19	0.006 ± 0.003	0.62	0.005 ± 0.002	120.03
Average	22.7	0.008 ± 0.002	1.31	0.011 ± 0.002	2.45	0.007 ± 0.002	0.92	0.006 ± 0.002	21.52

ISSN: 1743-422X