Figure 3From: Stereophysicochemical variability plots highlight conserved antigenic areas in Flavivirusesa) Local surface plot of the DV-Env SVP around residue 124 (which is highly variable but has been colored green here for clarity), illustrating how the residue forms part of a patch of variable (red) residues b) Removing part of the surface reveals how I124 lies above the highly conserved residues Cys60-121 (disulfide bonded) and Tyr59 that are distant in the sequence of the protein.Back to article page