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Figure 5 | Virology Journal

Figure 5

From: Origin-independent plasmid replication occurs in vaccinia virus cytoplasmic factories and requires all five known poxvirus replication factors

Figure 5

Visualization of plasmid replication in live HeLa cells. HeLa cells were transfected with pSV2-dhfr-8.32 containing tandem lac O repeats and infected with vGFP-lac I. Images were made at 5 min intervals starting at 5.5 h and ending at 10 h post infection. Selected images at the indicated time points are shown starting at 6 h time point. Arrow at 7.5 h time point indicates cytoplasmic site of replicated plasmid.

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Virology Journal

ISSN: 1743-422X