Figure 4From: Substitution of the premembrane and envelope protein genes of Modoc virus with the homologous sequences of West Nile virus generates a chimeric virus that replicates in vertebrate but not mosquito cellsDetection of cytopathic effect in Vero cells inoculated with MODV-WNV(prM-E). MODV-WNV(prM-E) and MODV that had been passaged twice in Vero cells were inoculated onto fresh monolayers of Vero cells that were monitored for 5 or 8 days, respectively. Mock-infected Vero cells that were incubated for 5 days were also included. Magnification = 100×.Back to article page