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Table 3 Reactivity of the mAb panel against FMDV/O nine isolates with r 1 value <0.3 in 2D-VNT

From: Characterization of monoclonal antibodies against foot-and-mouth disease virus serotype O and application in identification of antigenic variation in relation to vaccine strain selection

Viruses

F1140O2-5 VP3

F11VP2O-2 VP2

F12VP1O-2 Site 1b

F21-48 Site 1a,5

F21-64 Site 1a,5

F21-34 Site 2

F21-58 Site 2

F21-41 Site 3

F21-18 Near site 4

ECU/4/2010

0.10

1.07

0.49

1.42

0.45

-0.004

0.014

1.76

0.014

HKN/2/2011

1.21

-0.02

1.12

0.25

0.98

0.05

0.02

1.36

0.05

VIT/32/11

1.22

1.02

0.56

1.51

1.52

0.15

0.04

1.44

1.39

AFG/41/11

1.13

1.03

0.65

1.17

1.20

1.11

1.19

0.28

0.12

ETH/39/2009

1.20

1.05

0.39

1.2

1.2

1.15

1.19

1.10

1.05

UAE/9/2009

1.30

1.03

0.83

1.39

1.41

0.95

1.36

1.33

0.76

IRN/11/2006

1.07

1.02

0.49

1.13

1.10

0.99

1.10

1.08

1.06

TAW/12/98

1.58

0.80

0.06

1.57

1.63

1.55

1.61

0.07

-0.02

KUW/1/11

1.26

1.08

0.33

1.30

1.31

1.25

1.25

0.90

0.73

  1. The values are corrected OD values (RX in M& M) determined in the antigenic ELISA.
  2. Values <0.2: no reactivity; <0.5 weak reactivity.
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