Detection of hepatitis C virus (HCV) negative strand RNA and NS3 protein in peripheral blood mononuclear cells (PBMC): CD3+, CD14+ and CD19+

Table 1 Demographic, clinical and laboratory data of the patients

No.	Sex	Age (years)	ALAT (IU/l)	GGTP (IU/l)	Hist-pat	Cryoglob.	Genotype	Negative strand HCV RNA			NS3 positive cells (%)
No.	Sex	Age (years)	ALAT (IU/l)	GGTP (IU/l)	Hist-pat	Cryoglob.	Genotype	CD3⁺	CD14⁺	CD19⁺	CD3⁺	CD14⁺	CD19⁺
1	F	61	31	53	G9, S2	+	1b	-	+	-	17	-	-
2	M	52	35	nd	nd	-	1b	-	-	-	-	-	-
3	M	49	55	28	Cirrhosis	-	1b	-	-	-	8	-	-
4	M	59	81	58	G4, S3	-	1b	-	-	-	-	-	-
5	F	66	36	54	Cirrhosis	+	1b	-	-	-	7	1	1
6	F	63	55	29	G4, S2	+	1b	-	-	+	-	-	-
7	F	69	63	157	nd	+	1b	-	-	-	4	-	-
8	F	59	77	121	nd	-	1b	-	-	-	-	-	-
9	F	54	211	39	nd	-	1b	+	-	-	1	-	2
10	F	51	64	81	G9, S2	+	1b	+	-	-	-	-	-
11	M	50	50	85	Cirrhosis	+	3a	-	-	-	1	-	-
12	F	59	88	37	G5, S2	+	1b	-	-	-	-	2	4
13	F	54	71	91	Cirrhosis	-	1b	-	-	-	-	-	-
14	F	62	116	64	G5, S2	+	1b	-	+	-	2	2	1
15	F	58	158	58	G8, S2	-	1b	-	-	-	-	-	-
16	M	58	35	133	G7, S2	-	1b	-	-	-	-	2	-
17	F	62	26	97	Cirrhosis	-	1b	-	-	-	9	-	23
18	M	52	2165	401	acute h.	-	1b	-	-	-	5	1	-
19	M	30	147	142	G8, S2	-	1b	-	-	+	-	-	-
20	F	64	307	140	Cirrhosis	+	1b	-	-	-	-	-	-
21	F	58	63	109	Cirrhosis	-	1b	-	-	-	8	-	-
22	F	65	79	24	G4, S4	+	1b	-	-	-	-	-	1
23	M	34	90	54	G5, S1	-	1b	-	-	-	1	1	-
24	M	28	105	28	G5, S1	-	3a	-	-	-	-	-	-
25	F	42	44	80	Cirrhosis	-	1b	+	-	-	-	-	-
26	F	63	26	nd	nd	+	1b	-	+	-	-	-	-

Note: F, female; M, male; positive result (+); negative result (−); nd - not done; cryoglobulinemia (cryoglob.), histopatological finding (hist-pat.); G, grading (0–18); S, staging (0–4); (according to modified Knodell Score); [34]. Normal values of enzymes: ALAT (alanine aminotransferase): 10–52 F and <70 M; GGTP (gamma-glutamyltransferase): <43 F and < 73 M.

ISSN: 1743-422X