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Figure 6 | Virology Journal

Figure 6

From: Single dose of Glycoprotein K (gK)-deleted HSV-1 live-attenuated virus protects mice against lethal vaginal challenge with HSV-1 and HSV-2 and induces lasting T cell memory immune responses

Figure 6

Role of regulatory T cells in mock, HSV-vaccinated and HSV-vaccinated-challenged mice. (A) Representative contour plots showing the gating strategy for total FoxP3 and FoxP3 + CD25+ CD4+ Treg cells from splenocytes of a mock vaccinated mouse. (B & C) Percentages of total FoxP3 and CD25 + FoxP3+ CD4+ T-reg cells in three different groups of mice. A statistically significant difference (P < 0.05) was observed between HSV-vaccinated- and challenged as compared to vaccinated mice that were not challenged.

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Virology Journal

ISSN: 1743-422X