Vaccination of ferrets with a recombinant G glycoprotein subunit vaccine provides protection against Nipah virus disease for over 12 months

Table 3 Study 2: Genome detection in ferrets challenged at 434 days post vaccination

Ferret # - dose HeVsG	Ab titre to NiV at challenge	Eut dpc	Genome detected by PCR (dpc)						Virus positive tissues
Ferret # - dose HeVsG	Ab titre to NiV at challenge	Eut dpc	Oral swab	Rectal swab	Blood	Nasal wash	Urine	Tissues	Virus positive tissues
9-0	<4, <4	8	PM	-	PM	PM	PM	13/13	10/13
10-0	<4, <4	8	6, PM	6,PM	6, PM	6, PM	PM	13/13	10/13
11-4	32, 128	20	-	-	-	-	-	-	ND
12-4	32, 64	20	-	-	-	-	-	-	ND
13-20	16, 16	20	-	-	-	-	-	1/13	0/13
14-20	64, 128	20	-	-	-	6,8	-	^-	-
15-100	NC	na	NC	NC	NC	NC	NC	NC	NC
16-100	64, 64	20	-	-	-	-	-	-	ND

Ab antibody, Eut dpc day post challenge that ferrets were euthanized, PM post mortem, ND not done, NC no challenge; -, no viral RNA detected, na not applicable.

ISSN: 1743-422X