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Table 1 Appearance of anti-HBc and anti-HBs antibodies in C57BL/6 mice after HI of HBV plasmids

From: Inhibition of hepatitis B virus (HBV) gene expression and replication by HBx gene silencing in a hydrodynamic injection mouse model with a new clone of HBV genotype B

 

Anti-HBc antibodies

Anti-HBs antibodies

HBV clone

Day 1

day 7

Day 7

Day 28

Day 168

pAAV-HBV1.3 B

0/ 14

14/ 14

0/ 14

3/ 14

6/ 8

pAAV-HBV1.2

0/ 9

9/ 9

0/ 9

0/ 9

4/ 8

  1. The number of C57BL/6 mice in each group positive for anti-HBc or anti-HBs antibodies after injected hydrodynamically with 10 μg of pAAV-HBV1.3B or pAAV-HBV1.2 plasmids. All the mice with HBsAb are HBsAg negative.
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Virology Journal

ISSN: 1743-422X