Figure 3
From: Atypical hand-foot-mouth disease in children: a hospital-based prospective cohort study
The analysis of phylogeny is based on partial VP1 gene sequence (264–377 nucleotides). Clade I, is CVA6 strain HN421 (JQ964234), isolated from Henan, China in 2012. Clade II are the two circulating strains of CVA6 in Taiwan between 2004 and 2005 (EU908166, EU908170). Clade III includes the prototype CVA6 strain from the USA (AY421764), Japanese circulating strains in 2011 (AB649286- AB649291), 2009 Finland strains (FJ870502- FJ870508) and Taiwanese circulating strains in 2009–2010 (JN896786, JN896796, JQ390220, JQ390221) and the strains of the current study in 2010 (KC297130-KC297135).