Detection of specific HPV subtypes responsible for the pathogenesis of condylomata acuminata

Table 3 Comparing HPV DNA viral loads and RNA levels in whole wart tissue

Sample	HPV DNA viral load (copies/cell)					HPV RNA level (copies/μg RNA
	HPV6	HPV11	HPV16	HPV45	HPV52	HPV6	HPV11	HPV16	HPV45	HPV52
1	45.71	0	0*	0*	0	191.25	0	0*	0*	0
2	213.05	0.01	0.04	0	0	370	0	0	0	0
3	101.47	0	0*	0	0	0	0.34	0*	0	0
4	333.88	0	0*	0.03	0.05	186.77	26.88	0*	0	0
5	10974.83	0	115.18	0.35	0*	45.53	0	0	0	0.04*
6	13303.58	0	0.05	0	0	2047.98	0	0	0	0
7	218.29	0	0.03*	0	0	900.90	0	0*	0	0
8	604.56	0.01	0.03*	0	0	1341.49	0	0*	0	0
9	161.60	0	0.03	0	0	70.61	20.81	0	0	0
10	171.66	0	0.01*	0*	0*	5883.86	0	0*	0*	0*
11	279.68	0.01	0.18	0	0.02	856.98	43.52	0	0	0
12	0.01	4.31	172.88	0	0	0	51.15	17.20	0	0
13	571.85	0	0	0	0	-	-	-	-	-
14	48.47	0	0	0	0	-	-	-	-	-
15	0.22	0	0.41*	0	0	-	-	-	-	-
16	0	0	0.10	0	0.01	-	-	-	-	-
17	0	3.07	0.02	0	0	0	439.28	0	0	0
18	171.74	0	0.04*	0	0	0	0	0*	0	0
19	422.87	-	-	-	-	-	-	-	-	-
20	36.35	0.01	0	0	0	-	-	-	-	-
21	206.25	0.09	0.04	0	0	-	-	-	-	-
23	22.61	0.06	0*	0	0	-	-	-	-	-

HPV DNA viral loads (viral copies/cell) and RNA transcript levels (copies/μg RNA) were obtained by qPCR and qRT-PCR, respectively. (-) indicates that there was insufficient material for analyses. Samples containing HPV types previously determined as a likely contaminant (refer to Table 2) have been highlighted with an asterisk (*) and excluded from any further analysis.

ISSN: 1743-422X