Comparisons of the M1 genome segments and encoded μ2 proteins of different reovirus isolates

Table 5 Properties of different T3D and T3D-derived clones

			Positions of variation in T3D μ2
Virus isolate	Laboratory source	Virus factory morphology
			150	208	224	372
T3D	Nibert^a	globular^b	Gln	Ser^b	Glu	Ile
T3D	Coombs^a	globular	Gln	Ser	Glu	Ile
T3D	Schiff^a	globular	Gln	Ser	Glu	Ile
T3D	Tyler^a	globular	Gln	Ser	Glu	Ile
T3D	Cashdollar^c	filamentous^b	Arg	Pro^b	Glu	Met
T3D	Duncan^c	filamentous	Arg	Pro	Glu	Met
T3D	Shatkin	filamentous	Gln	Pro	Ala	Ile
T3D	ATCC	filamentous	Gln	Pro	Glu	Ile
tsC447	Coombs^c	filamentous	Gln	Pro	Glu	Ile
tsE320	Coombs^c	filamentous	Gln	Pro	Glu	Ile
tsG453	Coombs^c	filamentous	Gln	Pro	Glu	Ile

^a Origin traceable to B. N. Fields laboratory.
^b Reported in Parker et al. [23].
^c Origin traceable to W. K. Joklik laboratory; derived from T3D; sequences of tsC447 (GenBank accession no. AY428878), tsE320, and tsG453 are identical.

ISSN: 1743-422X