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  1. The entry of the SARS coronavirus (SCV) into cells is initiated by binding of its spike envelope glycoprotein (S) to a receptor, ACE2. We and others identified the receptor-binding domain (RBD) by using S frag...

    Authors: Samitabh Chakraborti, Ponraj Prabakaran, Xiaodong Xiao and Dimiter S Dimitrov

    Citation: Virology Journal 2005 2:73

    Content type: Research

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  2. Previous studies presented the quasispecies spectrum of the envelope region of dengue virus type 3 (DENV-3) from either clinical specimens or field-caught mosquitoes. However, the extent of sequence variation ...

    Authors: Day-Yu Chao, Chwan-Chuen King, Wei-Kung Wang, Wei-June Chen, Hui-Lin Wu and Gwong-Jen J Chang

    Citation: Virology Journal 2005 2:72

    Content type: Research

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  3. White spot syndrome virus (WSSV) is an important pathogen of the penaeid shrimp with high mortalities. In previous reports, Orf427 of WSSV is characterized as one of the three major latency-associated genes of WS...

    Authors: Liqun Lu, Hai Wang, Ivanus Manopo, Li Yu and Jimmy Kwang

    Citation: Virology Journal 2005 2:71

    Content type: Research

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  4. Much of the worlds' population is in active or imminent danger from established infectious pathogens, while sporadic and pandemic infections by these and emerging agents threaten everyone. RNA polymerases (RNApol

    Authors: Richard Sallie

    Citation: Virology Journal 2005 2:70

    Content type: Hypothesis

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  5. Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available.

    Authors: Martin J Vincent, Eric Bergeron, Suzanne Benjannet, Bobbie R Erickson, Pierre E Rollin, Thomas G Ksiazek, Nabil G Seidah and Stuart T Nichol

    Citation: Virology Journal 2005 2:69

    Content type: Research

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  6. Approximately 25% of hemophiliacs that were frequently exposed to blood clotting factor concentrates (CFCs) contaminated with human immunodeficiency virus (HIV) are presently HIV seronegative. In this study, w...

    Authors: Scott A Tenenbaum, Cindy A Morris, Steve S Alexander, Harris E McFerrin, Robert F Garry and Cindy A Leissinger

    Citation: Virology Journal 2005 2:65

    Content type: Research

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  7. The discovery and genome analysis of Acanthamoeba polyphaga Mimivirus, the largest known DNA virus, challenged much of the accepted dogma regarding viruses. Its particle size (>400 nm), genome length (1.2 million...

    Authors: Elodie Ghedin and Jean-Michel Claverie

    Citation: Virology Journal 2005 2:62

    Content type: Research

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  8. Herpes Simplex Virus (HSV) Genital Ulcer Disease (GUD) is an important public health problem, whose interaction with HIV results in mutually enhancing epidemics. Conventional methods for detecting HSV tend to ...

    Authors: Esther AN Aryee, Robin L Bailey, Angels Natividad-Sancho, Steve Kaye and Martin J Holland

    Citation: Virology Journal 2005 2:61

    Content type: Research

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  9. Around 400 million people worldwide are chronically infected with Hepatitis B virus (HBV). An estimated 10% of these chronic patients develop progressive liver damage including cirrhosis and Hepatocellular Car...

    Authors: Bernal León, Lizeth Taylor, Minor Vargas, Ronald B Luftig, Federico Albertazzi, Libia Herrero and Kirsten Visona

    Citation: Virology Journal 2005 2:60

    Content type: Research

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  10. Molecular epidemiologic studies have made significant contributions to measles surveillance activities by helping to identify source and transmission pathways of the virus. This report describes the genetic ch...

    Authors: Gulay Korukluoglu, Stephanie Liffick, Dalya Guris, Fumio Kobune, Paul A Rota, William J Bellini, Ali Ceylan and Meliksah Ertem

    Citation: Virology Journal 2005 2:58

    Content type: Research

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  11. The recent emergence of four new members of the paramyxovirus family has heightened the awareness of and re-energized research on new and emerging diseases. In particular, the high mortality and person to pers...

    Authors: Katharine N Bossart, Bruce A Mungall, Gary Crameri, Lin-Fa Wang, Bryan T Eaton and Christopher C Broder

    Citation: Virology Journal 2005 2:57

    Content type: Research

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  12. Human cytomegalovirus UL114 encodes a uracil-DNA glycosylase homolog that is highly conserved in all characterized herpesviruses that infect mammals. Previous studies demonstrated that the deletion of this noness...

    Authors: Mark N Prichard, Heather Lawlor, Gregory M Duke, Chengjun Mo, Zhaoti Wang, Melissa Dixon, George Kemble and Earl R Kern

    Citation: Virology Journal 2005 2:55

    Content type: Research

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  13. Human respiratory syncytial virus (HRSV) is an important respiratory pathogen primarily affecting infants, young children, transplant recipients and the elderly. The F protein is the only virion envelope prote...

    Authors: Patrick J Branigan, Changbao Liu, Nicole D Day, Lester L Gutshall, Robert T Sarisky and Alfred M Del Vecchio

    Citation: Virology Journal 2005 2:54

    Content type: Methodology

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  14. Giant double-stranded DNA viruses (such as record breaking Acanthamoeba polyphaga Mimivirus), with particle sizes of 0.2 to 0.6 μm, genomes of 300 kbp to 1.200 kbp, and commensurate complex gene contents, constit...

    Authors: Jean-Michel Claverie

    Citation: Virology Journal 2005 2:52

    Content type: Short report

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  15. A series of frameshift mutations within the 3a gene has been observed in culture-derived severe acute respiratory syndrome coronavirus (SARS-CoV). We report here that viral RNA from clinical samples obtained f...

    Authors: Timothy HP Tan, Timothy Barkham, Burtram C Fielding, Chih-Fong Chou, Shuo Shen, Seng Gee Lim, Wanjin Hong and Yee-Joo Tan

    Citation: Virology Journal 2005 2:51

    Content type: Short report

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  16. High-risk Human Papillomavirus (HPV) is the etiological agent associated with the majority of anogenital cancers. The primary HPV oncogenes, E6 and E7, undergo a complex splicing program resulting in protein p...

    Authors: Kulthida Vaeteewoottacharn, Siriphatr Chamutpong, Mathurose Ponglikitmongkol and Peter C Angeletti

    Citation: Virology Journal 2005 2:50

    Content type: Short report

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  17. The palindromic termini of parvoviruses have proven to play an essential role as origins of replication at different stages during the replication of their viral genome. Sequences from the left-end telomere of...

    Authors: Nanette Diffoot-Carlo, Lisandra Vélez-Pérez and Idaris de Jesús-Maldonado

    Citation: Virology Journal 2005 2:47

    Content type: Research

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  18. Respiratory syncytial virus (RSV) is the leading respiratory viral pathogen in young children worldwide. RSV disease is associated with acute airway obstruction (AO), long-term airway hyperresponsiveness (AHR)...

    Authors: Susana Chávez-Bueno, Asunción Mejías, Ana M Gómez, Kurt D Olsen, Ana M Ríos, Mónica Fonseca-Aten, Octavio Ramilo and Hasan S Jafri

    Citation: Virology Journal 2005 2:46

    Content type: Research

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  19. Plant viral diseases present major constraints to crop production. Effective sampling of the viruses infecting plants is required to facilitate their molecular study and is essential for the development of cro...

    Authors: Joseph Ndunguru, Nigel J Taylor, Jitender Yadav, Haytham Aly, James P Legg, Terry Aveling, Graham Thompson and Claude M Fauquet

    Citation: Virology Journal 2005 2:45

    Content type: Methodology

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  20. Crimean-Congo Hemorrhagic Fever virus (CCHFV), a member of the genus Nairovirus, family Bunyaviridae, is a tick-borne pathogen causing severe disease in humans. To better understand the CCHFV life cycle and explo...

    Authors: Sebastian Haferkamp, Lisa Fernando, Tino F Schwarz, Heinz Feldmann and Ramon Flick

    Citation: Virology Journal 2005 2:42

    Content type: Research

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  21. Hepatitis C virus (HCV) circulates as quasispecies (QS), whose evolution is associated with pathogenesis. Previous studies have suggested that the use of thermostable polymerases without proofreading function ...

    Authors: Stephen J Polyak, Daniel G Sullivan, Michael A Austin, James Y Dai, Margaret C Shuhart, Karen L Lindsay, Herbert L Bonkovsky, Adrian M Di Bisceglie, William M Lee, Chihiro Morishima and David R Gretch

    Citation: Virology Journal 2005 2:41

    Content type: Research

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  22. Undifferentiated nasopharyngeal carcinomas are rare in a majority of countries but they occur at a high incidence in South China and to a lesser extent in North Africa. They are constantly associated with the ...

    Authors: Abdelmajid Khabir, Hela Karray, Sandrine Rodriguez, Mathieu Rosé, Jamel Daoud, Mounir Frikha, Tahia Boudawara, Jaap Middeldorp, Rachid Jlidi and Pierre Busson

    Citation: Virology Journal 2005 2:39

    Content type: Research

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  23. Infection by human hepatitis C virus (HCV) is the principal cause of post-transfusion hepatitis and chronic liver diseases worldwide. A reliable in vitro culture system for the isolation and analysis of this viru...

    Authors: Dennis Revie, Ravi S Braich, David Bayles, Nickolas Chelyapov, Rafat Khan, Cheryl Geer, Richard Reisman, Ann S Kelley, John G Prichard and S Zaki Salahuddin

    Citation: Virology Journal 2005 2:37

    Content type: Research

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  24. Rice tungro bacilliform virus (RTBV) is a pararetrovirus, and a member of the family Caulimoviridae in the genus Badnavirus. RTBV has a long open reading frame that encodes a large polyprotein (P3). Pararetroviru...

    Authors: Philippe Marmey, Ana Rojas-Mendoza, Alexandre de Kochko, Roger N Beachy and Claude M Fauquet

    Citation: Virology Journal 2005 2:33

    Content type: Research

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  25. Avian metapneumoviruses (aMPV) cause an upper respiratory disease with low mortality, but high morbidity primarily in commercial turkeys. There are three types of aMPV (A, B, C) of which the C type is found on...

    Authors: Rene Alvarez and Bruce S Seal

    Citation: Virology Journal 2005 2:31

    Content type: Research

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  26. Poxviruses are important both as pathogens and as vaccine vectors. Poxvirus genomes (150–350 kb) consist of a single linear dsDNA molecule; the two polynucleotide strands are joined by short hairpin loops. The...

    Authors: Melissa Da Silva and Chris Upton

    Citation: Virology Journal 2005 2:30

    Content type: Research

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  27. Although PCR and RT-PCR provided a valuable approach for detection of pathogens, the high level of sensitivity of these assays also makes them prone to false positive results. In addition to cross-contaminatio...

    Authors: Steven B Kleiboeker

    Citation: Virology Journal 2005 2:29

    Content type: Methodology

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  28. We report the presence of three new O1 ElTor vibriophages named AS1, AS2 and AS3, isolated from the sewage and pond waters of the outskirts of Kolkata. A few phages, named AS4, with hexagonal heads and abnorma...

    Authors: Anindito Sen and Amar N Ghosh

    Citation: Virology Journal 2005 2:28

    Content type: Research

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  29. Phage N5 is one of the phages of Vibrio cholerae serovar O1 biotype El Tor (Ghosh, A. N., Ansari, M. Q., and Dutta, G. C. Isolation and morphological characterization of El Tor cholera phages. J. Gen. Virol. 70: ...

    Authors: Anindito Sen and Amar N Ghosh

    Citation: Virology Journal 2005 2:27

    Content type: Research

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  30. Early interaction of dengue virus and monocyte/macrophages could be an important feature for virus dissemination after its initial entry via the mosquito vector. Since ultrastructural analysis of this interact...

    Authors: Jesus A Mosquera, Juan Pablo Hernandez, Nereida Valero, Luz Marina Espina and German J Añez

    Citation: Virology Journal 2005 2:26

    Content type: Research

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