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  1. Molecular epidemiologic studies have made significant contributions to measles surveillance activities by helping to identify source and transmission pathways of the virus. This report describes the genetic ch...

    Authors: Gulay Korukluoglu, Stephanie Liffick, Dalya Guris, Fumio Kobune, Paul A Rota, William J Bellini, Ali Ceylan and Meliksah Ertem

    Citation: Virology Journal 2005 2:58

    Content type: Research

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  2. The recent emergence of four new members of the paramyxovirus family has heightened the awareness of and re-energized research on new and emerging diseases. In particular, the high mortality and person to pers...

    Authors: Katharine N Bossart, Bruce A Mungall, Gary Crameri, Lin-Fa Wang, Bryan T Eaton and Christopher C Broder

    Citation: Virology Journal 2005 2:57

    Content type: Research

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  3. Human cytomegalovirus UL114 encodes a uracil-DNA glycosylase homolog that is highly conserved in all characterized herpesviruses that infect mammals. Previous studies demonstrated that the deletion of this noness...

    Authors: Mark N Prichard, Heather Lawlor, Gregory M Duke, Chengjun Mo, Zhaoti Wang, Melissa Dixon, George Kemble and Earl R Kern

    Citation: Virology Journal 2005 2:55

    Content type: Research

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  4. Human respiratory syncytial virus (HRSV) is an important respiratory pathogen primarily affecting infants, young children, transplant recipients and the elderly. The F protein is the only virion envelope prote...

    Authors: Patrick J Branigan, Changbao Liu, Nicole D Day, Lester L Gutshall, Robert T Sarisky and Alfred M Del Vecchio

    Citation: Virology Journal 2005 2:54

    Content type: Methodology

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  5. Giant double-stranded DNA viruses (such as record breaking Acanthamoeba polyphaga Mimivirus), with particle sizes of 0.2 to 0.6 μm, genomes of 300 kbp to 1.200 kbp, and commensurate complex gene contents, constit...

    Authors: Jean-Michel Claverie

    Citation: Virology Journal 2005 2:52

    Content type: Short report

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  6. A series of frameshift mutations within the 3a gene has been observed in culture-derived severe acute respiratory syndrome coronavirus (SARS-CoV). We report here that viral RNA from clinical samples obtained f...

    Authors: Timothy HP Tan, Timothy Barkham, Burtram C Fielding, Chih-Fong Chou, Shuo Shen, Seng Gee Lim, Wanjin Hong and Yee-Joo Tan

    Citation: Virology Journal 2005 2:51

    Content type: Short report

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  7. High-risk Human Papillomavirus (HPV) is the etiological agent associated with the majority of anogenital cancers. The primary HPV oncogenes, E6 and E7, undergo a complex splicing program resulting in protein p...

    Authors: Kulthida Vaeteewoottacharn, Siriphatr Chamutpong, Mathurose Ponglikitmongkol and Peter C Angeletti

    Citation: Virology Journal 2005 2:50

    Content type: Short report

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  8. The palindromic termini of parvoviruses have proven to play an essential role as origins of replication at different stages during the replication of their viral genome. Sequences from the left-end telomere of...

    Authors: Nanette Diffoot-Carlo, Lisandra Vélez-Pérez and Idaris de Jesús-Maldonado

    Citation: Virology Journal 2005 2:47

    Content type: Research

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  9. Respiratory syncytial virus (RSV) is the leading respiratory viral pathogen in young children worldwide. RSV disease is associated with acute airway obstruction (AO), long-term airway hyperresponsiveness (AHR)...

    Authors: Susana Chávez-Bueno, Asunción Mejías, Ana M Gómez, Kurt D Olsen, Ana M Ríos, Mónica Fonseca-Aten, Octavio Ramilo and Hasan S Jafri

    Citation: Virology Journal 2005 2:46

    Content type: Research

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  10. Plant viral diseases present major constraints to crop production. Effective sampling of the viruses infecting plants is required to facilitate their molecular study and is essential for the development of cro...

    Authors: Joseph Ndunguru, Nigel J Taylor, Jitender Yadav, Haytham Aly, James P Legg, Terry Aveling, Graham Thompson and Claude M Fauquet

    Citation: Virology Journal 2005 2:45

    Content type: Methodology

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  11. Crimean-Congo Hemorrhagic Fever virus (CCHFV), a member of the genus Nairovirus, family Bunyaviridae, is a tick-borne pathogen causing severe disease in humans. To better understand the CCHFV life cycle and explo...

    Authors: Sebastian Haferkamp, Lisa Fernando, Tino F Schwarz, Heinz Feldmann and Ramon Flick

    Citation: Virology Journal 2005 2:42

    Content type: Research

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  12. Hepatitis C virus (HCV) circulates as quasispecies (QS), whose evolution is associated with pathogenesis. Previous studies have suggested that the use of thermostable polymerases without proofreading function ...

    Authors: Stephen J Polyak, Daniel G Sullivan, Michael A Austin, James Y Dai, Margaret C Shuhart, Karen L Lindsay, Herbert L Bonkovsky, Adrian M Di Bisceglie, William M Lee, Chihiro Morishima and David R Gretch

    Citation: Virology Journal 2005 2:41

    Content type: Research

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  13. Undifferentiated nasopharyngeal carcinomas are rare in a majority of countries but they occur at a high incidence in South China and to a lesser extent in North Africa. They are constantly associated with the ...

    Authors: Abdelmajid Khabir, Hela Karray, Sandrine Rodriguez, Mathieu Rosé, Jamel Daoud, Mounir Frikha, Tahia Boudawara, Jaap Middeldorp, Rachid Jlidi and Pierre Busson

    Citation: Virology Journal 2005 2:39

    Content type: Research

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  14. Infection by human hepatitis C virus (HCV) is the principal cause of post-transfusion hepatitis and chronic liver diseases worldwide. A reliable in vitro culture system for the isolation and analysis of this viru...

    Authors: Dennis Revie, Ravi S Braich, David Bayles, Nickolas Chelyapov, Rafat Khan, Cheryl Geer, Richard Reisman, Ann S Kelley, John G Prichard and S Zaki Salahuddin

    Citation: Virology Journal 2005 2:37

    Content type: Research

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  15. Rice tungro bacilliform virus (RTBV) is a pararetrovirus, and a member of the family Caulimoviridae in the genus Badnavirus. RTBV has a long open reading frame that encodes a large polyprotein (P3). Pararetroviru...

    Authors: Philippe Marmey, Ana Rojas-Mendoza, Alexandre de Kochko, Roger N Beachy and Claude M Fauquet

    Citation: Virology Journal 2005 2:33

    Content type: Research

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  16. Avian metapneumoviruses (aMPV) cause an upper respiratory disease with low mortality, but high morbidity primarily in commercial turkeys. There are three types of aMPV (A, B, C) of which the C type is found on...

    Authors: Rene Alvarez and Bruce S Seal

    Citation: Virology Journal 2005 2:31

    Content type: Research

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  17. Poxviruses are important both as pathogens and as vaccine vectors. Poxvirus genomes (150–350 kb) consist of a single linear dsDNA molecule; the two polynucleotide strands are joined by short hairpin loops. The...

    Authors: Melissa Da Silva and Chris Upton

    Citation: Virology Journal 2005 2:30

    Content type: Research

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  18. Although PCR and RT-PCR provided a valuable approach for detection of pathogens, the high level of sensitivity of these assays also makes them prone to false positive results. In addition to cross-contaminatio...

    Authors: Steven B Kleiboeker

    Citation: Virology Journal 2005 2:29

    Content type: Methodology

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  19. We report the presence of three new O1 ElTor vibriophages named AS1, AS2 and AS3, isolated from the sewage and pond waters of the outskirts of Kolkata. A few phages, named AS4, with hexagonal heads and abnorma...

    Authors: Anindito Sen and Amar N Ghosh

    Citation: Virology Journal 2005 2:28

    Content type: Research

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  20. Phage N5 is one of the phages of Vibrio cholerae serovar O1 biotype El Tor (Ghosh, A. N., Ansari, M. Q., and Dutta, G. C. Isolation and morphological characterization of El Tor cholera phages. J. Gen. Virol. 70: ...

    Authors: Anindito Sen and Amar N Ghosh

    Citation: Virology Journal 2005 2:27

    Content type: Research

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  21. Early interaction of dengue virus and monocyte/macrophages could be an important feature for virus dissemination after its initial entry via the mosquito vector. Since ultrastructural analysis of this interact...

    Authors: Jesus A Mosquera, Juan Pablo Hernandez, Nereida Valero, Luz Marina Espina and German J Añez

    Citation: Virology Journal 2005 2:26

    Content type: Research

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  22. Rotavirus genotyping is performed by using reverse transcription PCR with type-specific-primers. Because the high rotavirus mutation rate generates an extensive genomic variation, different G-type-specific pri...

    Authors: Mustafizur Rahman, Rasheda Sultana, Goutam Podder, Abu SG Faruque, Jelle Matthijnssens, Khalequz Zaman, Robert F Breiman, David A Sack, Marc Van Ranst and Tasnim Azim

    Citation: Virology Journal 2005 2:24

    Content type: Research

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  23. Replication of the vaccinia virus genome occurs in cytoplasmic factory areas and is dependent on the virus-encoded DNA polymerase and at least four additional viral proteins. DNA synthesis appears to start nea...

    Authors: Frank S De Silva and Bernard Moss

    Citation: Virology Journal 2005 2:23

    Content type: Research

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  24. Poxviruses encode a range of immunomodulatory genes to subvert or evade the challenges posed by the innate and adaptive immune responses. However, the inactivated poxviruses possessed immunostimulating capacit...

    Authors: Abdel-Aziz S Abu-EL-Saad and Ahmed S Abdel-Moneim

    Citation: Virology Journal 2005 2:22

    Content type: Research

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  25. Cassava is infected by numerous geminiviruses in Africa and India that cause devastating losses to poor farmers. We here describe the molecular diversity of seven representative cassava mosaic geminiviruses (C...

    Authors: J Ndunguru, JP Legg, TAS Aveling, G Thompson and CM Fauquet

    Citation: Virology Journal 2005 2:21

    Content type: Research

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  26. Amino acid sequence analyses indicate that the Soilborne wheat mosaic virus (SBWMV) 19K protein is a cysteine-rich protein (CRP) and shares sequence homology with CRPs derived from furo-, hordei-, peclu- and tobr...

    Authors: Jeannie Te, Ulrich Melcher, Amanda Howard and Jeanmarie Verchot-Lubicz

    Citation: Virology Journal 2005 2:18

    Content type: Research

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  27. The interferon (IFN)-induced, dsRNA-dependent serine/threonine protein kinase, PKR, plays a key regulatory role in the IFN-mediated anti-viral response by blocking translation in the infected cell by phosphory...

    Authors: Liliana Endo-Munoz, Tammra Warby, David Harrich and Nigel A J McMillan

    Citation: Virology Journal 2005 2:17

    Content type: Research

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  28. We examined the association and interaction between maternal viral load and antibodies in vertical transmission of HIV in a non-randomized prospective study of 43 HIV-1 infected pregnant women who attended the...

    Authors: Paul Kamara, Loyda Melendez-Guerrero, Miguel Arroyo, Heidi Weiss and Pauline Jolly

    Citation: Virology Journal 2005 2:15

    Content type: Research

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  29. Recent studies have shown that gamma interferon (IFN-γ) synergizes with the innate IFNs (IFN-α and IFN-β) to inhibit herpes simplex virus type 1 (HSV-1) replication in vitro. To determine whether this phenomenon ...

    Authors: Bruno Sainz Jr, Heather L LaMarca, Robert F Garry and Cindy A Morris

    Citation: Virology Journal 2005 2:14

    Content type: Research

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  30. Human sapovirus (SaV), an agent of human gastroenteritis, cannot be grown in cell culture, but expression of the recombinant capsid protein (rVP1) in a baculovirus expression system results in the formation of...

    Authors: Grant S Hansman, Kazuhiko Katayama, Tomoichiro Oka, Katsuro Natori and Naokazu Takeda

    Citation: Virology Journal 2005 2:13

    Content type: Research

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  31. Tula hantavirus carrying recombinant S RNA segment (recTULV) grew in a cell culture to the same titers as the original cell adapted variant but presented no real match to the parental virus. Our data showed th...

    Authors: Angelina Plyusnina and Alexander Plyusnin

    Citation: Virology Journal 2005 2:12

    Content type: Research

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  32. Oral infection of infant macaques with simian immunodeficiency virus (SIV) is a useful animal model to test interventions to reduce postnatal HIV transmission via breast-feeding. We previously demonstrated tha...

    Authors: Jennifer L Greenier, Koen KA Van Rompay, David Montefiori, Patricia Earl, Bernard Moss and Marta L Marthas

    Citation: Virology Journal 2005 2:11

    Content type: Research

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  33. Immunor (IM28), an analog of dehydroepiandrosterone (DHEA), inhibits human immunodeficiency virus type-1 (HIV-1) by inhibiting reverse transcriptase. We assessed the ability of IM28 to inhibit the cell-cell fu...

    Authors: Donatien Mavoungou, Virginie Poaty-Mavoungou, Marie-Yvonne Akoume, Brice Ongali and Elie Mavoungou

    Citation: Virology Journal 2005 2:9

    Content type: Research

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  34. Inteins are "protein introns" that remove themselves from their host proteins through an autocatalytic protein-splicing. After their discovery, inteins have been quickly identified in all domains of life, but ...

    Authors: Hiroyuki Ogata, Didier Raoult and Jean-Michel Claverie

    Citation: Virology Journal 2005 2:8

    Content type: Research

    Published on: