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  1. Since 2005 highly pathogenic (HP) avian influenza A H5N1 viruses have spread from Asia to Africa and Europe infecting poultry, humans and wild birds. HP H5N1 virus was isolated in Denmark for the first time in...

    Authors: Karoline Bragstad, Poul H Jørgensen, Kurt Handberg, Anne S Hammer, Susanne Kabell and Anders Fomsgaard

    Citation: Virology Journal 2007 4:43

    Content type: Research

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  2. Human influenza viruses are known to bind to sialic acid linked α2-6 to galactose, but the binding specificity beyond that linkage has not been systematically examined. H3N2 human influenza isolates lost bindi...

    Authors: Kshama Kumari, Shelly Gulati, David F Smith, Upma Gulati, Richard D Cummings and Gillian M Air

    Citation: Virology Journal 2007 4:42

    Content type: Research

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  3. La Crosse virus (LACV), family Bunyaviridae, is a mosquito-borne virus recognized as a major cause of pediatric encephalitis in North America with 70–130 symptomatic cases each year. The virus was first identifie...

    Authors: Richard S Bennett, David R Ton, Christopher T Hanson, Brian R Murphy and Stephen S Whitehead

    Citation: Virology Journal 2007 4:41

    Content type: Research

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  4. The human rhinoviruses (HRV) are one of the most common and diverse respiratory pathogens of humans. Over 100 distinct HRV serotypes are known, yet only 6 genomes are available. Due to the paucity of HRV genom...

    Authors: Amy L Kistler, Dale R Webster, Silvi Rouskin, Vince Magrini, Joel J Credle, David P Schnurr, Homer A Boushey, Elaine R Mardis, Hao Li and Joseph L DeRisi

    Citation: Virology Journal 2007 4:40

    Content type: Research

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  5. Chloroquine is a 4-aminoquinoline previously used in malaria therapy and now becoming an emerging investigational antiviral drug due to its broad spectrum of antiviral activities. To explore whether the low pH...

    Authors: Livia Di Trani, Andrea Savarino, Laura Campitelli, Sandro Norelli, Simona Puzelli, Daniela D'Ostilio, Edoardo Vignolo, Isabella Donatelli and Antonio Cassone

    Citation: Virology Journal 2007 4:39

    Content type: Research

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  6. Plasmodiophorids and chytrids are zoosporic parasites of algae and land plant and are distributed worldwide. There are 35 species belonging to the order Plasmodiophorales and three species, Polymyxa betae, P. gra...

    Authors: Jeanmarie Verchot Lubicz, Charles M Rush, Mark Payton and Terry Colberg

    Citation: Virology Journal 2007 4:37

    Content type: Research

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  7. Hepatitis B virus (HBV) replication has been reported to be involved in many extrahepatic viral disorders; however, the mechanism by which HBV is trans-infected into extrahepatic tissues such as HBV associated...

    Authors: Qifei Rong, Jun Huang, Enben Su, Jun Li, Jianyong Li, Lili Zhang and Kejiang Cao

    Citation: Virology Journal 2007 4:36

    Content type: Research

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  8. The role of humoral immunity in hepatitis C virus (HCV) infection is poorly understood. Nevertheless, there is increasing interest in characterizing the neutralizing antibodies in the serum of HCV-infected pat...

    Authors: Carole Fournier, Gilles Duverlie, Catherine François, Aurelie Schnuriger, Sarah Dedeurwaerder, Etienne Brochot, Dominique Capron, Czeslaw Wychowski, Vincent Thibault and Sandrine Castelain

    Citation: Virology Journal 2007 4:35

    Content type: Methodology

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  9. Infectious salmon anaemia (ISA) virus (ISAV), an important pathogen of fish that causes disease accompanied by high mortality in marine-farmed Atlantic salmon, is the only species in the genus Isavirus, one of th...

    Authors: Frederick SB Kibenge, Hongtao Xu, Molly JT Kibenge, Biao Qian and Tomy Joseph

    Citation: Virology Journal 2007 4:34

    Content type: Research

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  10. Human papillomavirus (HPV) has a causal role in cervical cancer with almost half a million new cases occurring each year. Presence of the carcinogenic HPV is necessary for the development of the invasive carci...

    Authors: Manuel Angulo and Antonio Carvajal-Rodríguez

    Citation: Virology Journal 2007 4:33

    Content type: Research

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  11. Severe acute respiratory syndrome (SARS) caused a large outbreak of pneumonia in Beijing, China, in 2003. Reverse transcriptase polymerase chain reaction (RT-PCR) was used to detect and quantify SARS-CoV in 93...

    Authors: Zhongping He, Hui Zhuang, Chunhui Zhao, Qingming Dong, Guoai Peng and Dominic E Dwyer

    Citation: Virology Journal 2007 4:32

    Content type: Research

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  12. The genomes of both long-genome (> 200 Kb) bacteriophages and long-genome eukaryotic viruses have cellular gene homologs whose selective advantage is not explained. These homologs add genomic and possibly bioc...

    Authors: Philip Serwer

    Citation: Virology Journal 2007 4:30

    Content type: Hypothesis

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  13. Human papillomavirus type-16 (HPV-16) infects mucosal epithelium and is the most common type found in cervical cancer. HPV-5 infects cornified epithelium and is the most common type found on normal skin and be...

    Authors: Nitesh Mistry, Monika Simonsson and Magnus Evander

    Citation: Virology Journal 2007 4:27

    Content type: Short report

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  14. Antigenic chimeric viruses have previously been generated in which the structural genes of recombinant dengue virus type 4 (rDEN4) have been replaced with those derived from DEN2 or DEN3. Two vaccine candidate...

    Authors: Joseph E Blaney Jr., Neeraj S Sathe, Christopher T Hanson, Cai Yen Firestone, Brian R Murphy and Stephen S Whitehead

    Citation: Virology Journal 2007 4:23

    Content type: Research

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  15. Coronaviruses are an important cause of infectious diseases in humans, including severe acute respiratory syndrome (SARS), and have the continued potential for emergence from animal species. A major factor in ...

    Authors: Victor C Chu, Lisa J McElroy, Jed M Aronson, Trisha J Oura, Carole E Harbison, Beverley E Bauman and Gary R Whittaker

    Citation: Virology Journal 2007 4:20

    Content type: Research

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  16. The methylation status at the human papilloma virus (HPV) genome found in pre-invasive and invasive cervical lesions suggests that neoplastic transformation can be suppressed by gene hypermethylation, whereas ...

    Authors: Erick de la Cruz-Hernández, Enrique Pérez-Cárdenas, Adriana Contreras-Paredes, David Cantú, Alejandro Mohar, Marcela Lizano and Alfonso Dueñas-González

    Citation: Virology Journal 2007 4:18

    Content type: Research

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  17. Japanese encephalitis virus (JEV), a member of the family Flaviviridae, is an important mosquito-borne human pathogen. Its envelope glycoprotein (E) is the major determinant of the pathogenicity and host immune r...

    Authors: Fuquan Zhang, Wenyu Ma, Li Zhang, Marlen Aasa-Chapman and Hongyi Zhang

    Citation: Virology Journal 2007 4:17

    Content type: Research

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  18. HCV is one of the major health problems in Egypt, where it is highly prevalent. Genotype 4 is the most common genotype of HCV and its response to treatment is still a controversy.

    Authors: Abdel Rahman N Zekri, Hanaa M Alam El-Din, Abeer A Bahnassy, Mohsen M Khaled, Ashraf Omar, Inas Fouad, Mahmoud El-Hefnewi, Fouad Thakeb and Mostafa El-Awady

    Citation: Virology Journal 2007 4:16

    Content type: Research

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  19. This report describes the genetic characterization of 297 wild-type measles viruses that were isolated in 24 provinces of China between 1995 and 2003. Phylogenetic analysis of the N gene sequences showed that ...

    Authors: Yan Zhang, Zhen Zhu, Paul A Rota, Xiaohong Jiang, Jiayu Hu, Jianguo Wang, Wei Tang, Zhenying Zhang, Congyong Li, Changyin Wang, Tongzhan Wang, Lei Zheng, Hong Tian, Hua Ling, Chunfang Zhao, Yan Ma…

    Citation: Virology Journal 2007 4:14

    Content type: Research

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  20. Infectious salmon anaemia (ISA) virus (ISAV) is a fish orthomyxovirus that has recently been assigned to the new genus Isavirus within the family Orthomyxoviridae. It possesses the major functional characteristic...

    Authors: Samuel T Workenhe, Dorota W Wadowska, Glenda M Wright, Molly JT Kibenge and Frederick SB Kibenge

    Citation: Virology Journal 2007 4:13

    Content type: Short report

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  21. The extraordinary morphologies of viruses infecting hyperthermophilic archaea clearly distinguish them from bacterial and eukaryotic viruses. Moreover, their genomes code for proteins that to a large extend ha...

    Authors: Jenny Keller, Nicolas Leulliot, Christian Cambillau, Valérie Campanacci, Stéphanie Porciero, David Prangishvili, Patrick Forterre, Diego Cortez, Sophie Quevillon-Cheruel and Herman van Tilbeurgh

    Citation: Virology Journal 2007 4:12

    Content type: Research

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  22. Members of the family Iridoviridae can cause severe diseases resulting in significant economic and environmental losses. Very little is known about how iridoviruses cause disease in their host. In the present stu...

    Authors: Heather E Eaton, Julie Metcalf, Emily Penny, Vasily Tcherepanov, Chris Upton and Craig R Brunetti

    Citation: Virology Journal 2007 4:11

    Content type: Research

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  23. Whitefly-transmitted geminiviruses (genus Begomovirus) are phytopathogens that cause heavy losses to crops worldwide. Efforts to engineer resistance against these viruses are focused mainly on silencing of comple...

    Authors: Muhammad Mubin, Shahid Mansoor, Mazhar Hussain and Yusuf Zafar

    Citation: Virology Journal 2007 4:10

    Content type: Short report

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  24. Hepatitis B virus (HBV) is a small DNA-containing virus with 4 genes, C, S, X and P. The S gene codes for the surface antigen (HBsAg), which contains the "a" determinant, the main region for induction of a protec...

    Authors: Martha-Eugenia Ruiz-Tachiquín, Hilda-Alicia Valdez-Salazar, Vicencio Juárez-Barreto, Margarita Dehesa-Violante, Javier Torres, Onofre Muñoz-Hernández and Ma-Teresa Alvarez-Muñoz

    Citation: Virology Journal 2007 4:6

    Content type: Research

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  25. Human immunodeficiency virus (HIV-1) exclusively selects and utilizes tRNALys,3 as the primer for initiation of reverse transcription. Several elements within the TΨC stem loop of tRNALys,3 are postulated to be i...

    Authors: Wanfeng Yu, Anna McCulley and Casey D Morrow

    Citation: Virology Journal 2007 4:5

    Content type: Research

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  26. Human immunodeficiency virus (HIV-1) preferentially selects tRNALys,3 as the primer for reverse transcription. HIV-1 can be forced to select alternative tRNAs through mutation in the primer-binding site (PBS) and...

    Authors: Na Ni, Wenqin Xu and Casey D Morrow

    Citation: Virology Journal 2007 4:4

    Content type: Research

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  27. Herpes simplex virus type 2 (HSV-2) is a major cofactor of human immunodeficiency virus type 1 (HIV-1) sexual acquisition and transmission. In the present study, we investigated whether HIV-1 and HSV-2 may int...

    Authors: Jérôme LeGoff, Hicham Bouhlal, Maxime Lecerf, Christophe Klein, Hakim Hocini, Ali Si-Mohamed, Martin Muggeridge and Laurent Bélec

    Citation: Virology Journal 2007 4:2

    Content type: Research

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  28. Nipah virus (NiV) is an emerging paramyxovirus distinguished by its ability to cause fatal disease in both animal and human hosts. Together with Hendra virus (HeV), they comprise the genus Henipavirus in the Para...

    Authors: Jared R Patch, Gary Crameri, Lin-Fa Wang, Bryan T Eaton and Christopher C Broder

    Citation: Virology Journal 2007 4:1

    Content type: Research

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  29. The genome of coronaviruses contains structural and non-structural genes, including several so-called accessory genes. All group 1b coronaviruses encode a single accessory protein between the spike and envelop...

    Authors: Ronald Dijkman, Maarten F Jebbink, Berry Wilbrink, Krzysztof Pyrc, Hans L Zaaijer, Philip D Minor, Sally Franklin, Ben Berkhout, Volker Thiel and Lia van der Hoek

    Citation: Virology Journal 2006 3:106

    Content type: Research

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  30. Herpes simplex virus (HSV) can utilize multiple pathways to enter host cells. The factors that determine which route is taken are not clear. Chinese hamster ovary (CHO) cells that express glycoprotein D (gD)-b...

    Authors: Mark G Delboy, Jennifer L Patterson, Aimee M Hollander and Anthony V Nicola

    Citation: Virology Journal 2006 3:105

    Content type: Research

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  31. HIV-1 entry into cells is a multifaceted process involving target cell CD4 and the chemokine receptors, CXCR4 or CCR5. The lipid composition of the host cell plays a significant role in the HIV fusion process ...

    Authors: Sherimay Ablan, Satinder S Rawat, Mathias Viard, Ji Ming Wang, Anu Puri and Robert Blumenthal

    Citation: Virology Journal 2006 3:104

    Content type: Research

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  32. The duration of treatment for HCV infection is partly indicated by the genotype of the virus. For studies of disease transmission, vaccine design, and surveillance for novel variants, subtype-level classificat...

    Authors: Peter T Hraber, William Fischer, William J Bruno, Thomas Leitner and Carla Kuiken

    Citation: Virology Journal 2006 3:103

    Content type: Research

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  33. Matrix protein 2 (M2) is an integral tetrameric membrane protein of influenza A virus (IAV). Its ectodomain (M2e) shows remarkably little diversity amongst human IAV strains. As M2e-specific antibodies (Abs) h...

    Authors: JingQi Feng, Manxin Zhang, Krystyna Mozdzanowska, Darya Zharikova, Henry Hoff, William Wunner, Robert B Couch and Walter Gerhard

    Citation: Virology Journal 2006 3:102

    Content type: Research

    Published on: