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  1. The most often used mumps vaccine strains Jeryl Lynn (JL), RIT4385, Urabe-AM9, L-Zagreb and L-3 differ in immunogenicity and reactogenicity. Previous analyses showed that JL, Urabe-AM9 and L-3 are genetically ...

    Authors: Tanja Kosutic-Gulija, Dubravko Forcic, Maja Šantak, Ana Ramljak, Sanja Mateljak-Lukacevic and Renata Mazuran

    Citation: Virology Journal 2008 5:79

    Content type: Research

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  2. Pre-treatment HCV quasispecies complexity and diversity may predict response to interferon based anti-viral therapy. The objective of this study was to retrospectively (1) examine temporal changes in quasispec...

    Authors: Isabelle Moreau, John Levis, Orla Crosbie, Elizabeth Kenny-Walsh and Liam J Fanning

    Citation: Virology Journal 2008 5:78

    Content type: Research

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  3. The emergence of high pathogenicity strains of Influenza A virus in a variety of human and animal hosts, with wide geographic distribution, has highlighted the importance of rapid identification and subtyping ...

    Authors: Alejandra Castillo Alvarez, Marion EG Brunck, Victoria Boyd, Richard Lai, Elena Virtue, Wenbin Chen, Cheryl Bletchly, Hans G Heine and Ross Barnard

    Citation: Virology Journal 2008 5:77

    Content type: Research

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  4. Presumptive phage particles associated with Xylella fastidiosa strain Temecula-1 grown in PW broth were observed by transmission electron microscopy (TEM) in ultrathin sections of bacterial cell-containing low sp...

    Authors: Jianchi Chen and Edwin L Civerolo

    Citation: Virology Journal 2008 5:75

    Content type: Short report

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  5. There is a significant requirement for the development and acquisition of reagents that will facilitate effective diagnosis, treatment, and prevention of Lassa fever. In this regard, recombinant Lassa virus (L...

    Authors: Luis M Branco, Alex Matschiner, Joseph N Fair, Augustine Goba, Darryl B Sampey, Philip J Ferro, Kathleen A Cashman, Randal J Schoepp, Robert B Tesh, Daniel G Bausch, Robert F Garry and Mary C Guttieri

    Citation: Virology Journal 2008 5:74

    Content type: Research

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  6. The construction of expression vectors derived from the human adenovirus type 5 (Ad5), usually based on homologous recombination, is time consuming as a shuttle plasmid has to be selected before recombination ...

    Authors: Laurent Mailly, Charlotte Boulade-Ladame, Georges Orfanoudakis and François Deryckere

    Citation: Virology Journal 2008 5:73

    Content type: Short report

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  7. Hepatitis C virus isolates have been classified into six main genotypes and a variable number of subtypes within each genotype, mainly based on phylogenetic analysis. Analyses of the genetic relationship among...

    Authors: Maria A Bracho, Verónica Saludes, Elisa Martró, Ana Bargalló, Fernando González-Candelas and Vicent Ausina

    Citation: Virology Journal 2008 5:72

    Content type: Research

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  8. The global spread of the highly pathogenic avian influenza H5N1 virus has stimulated interest in a better understanding of the mechanisms of H5N1 dispersal, including the potential role of migratory birds as c...

    Authors: Hon S Ip, Paul L Flint, J Christian Franson, Robert J Dusek, Dirk V Derksen, Robert E Gill Jr., Craig R Ely, John M Pearce, Richard B Lanctot, Steven M Matsuoka, David B Irons, Julian B Fischer, Russell M Oates, Margaret R Petersen, Thomas F Fondell, Deborah A Rocque…

    Citation: Virology Journal 2008 5:71

    Content type: Research

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  9. Human metapneumovirus (hMPV) infection can cause acute lower respiratory tract illness in infants, the immunocompromised, and the elderly. Currently there are no licensed preventative measures for hMPV infecti...

    Authors: Jeanne H Schickli, Jasmine Kaur, Mia MacPhail, Jeanne M Guzzetta, Richard R Spaete and Roderick S Tang

    Citation: Virology Journal 2008 5:69

    Content type: Research

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  10. The NV1020 oncolytic herpes simplex virus type-1 has shown significant promise for the treatment of many different types of tumors in experimental animal models and human trials. Previously, we described the c...

    Authors: Anna Israyelyan, Vladimir N Chouljenko, Abolghasem Baghian, Andrew T David, Michael T Kearney and Konstantin G Kousoulas

    Citation: Virology Journal 2008 5:68

    Content type: Research

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  11. Central to cellular transformation caused by human papillomaviruses (HPVs) is the ability of E6 proteins to target cellular p53 and proteins containing PDZ domains, including MAGI-3, for degradation. The aim o...

    Authors: Julia Ainsworth, Miranda Thomas, Lawrence Banks, Francois Coutlee and Greg Matlashewski

    Citation: Virology Journal 2008 5:67

    Content type: Research

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  12. Selenium (Se) deficiency plays an important role in viral pathogenesis. To understand the effects of Se deficiency on West Nile virus (WNV) infection, we analyzed cytopathogenicity, apoptosis and viral replica...

    Authors: Saguna Verma, Yanira Molina, Yeung Y Lo, Bruce Cropp, Cheynie Nakano, Richard Yanagihara and Vivek R Nerurkar

    Citation: Virology Journal 2008 5:66

    Content type: Research

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  13. During the early and mid part of 20th century, several reports described the therapeutic effects of N-methylisatin-β-Thiosemicarbazone (MIBT) against pox viruses, Maloney leukemia viruses and recently against HIV...

    Authors: Liba Sebastian, Anita Desai, Madhusudana N Shampur, Yogeeswari Perumal, D Sriram and Ravi Vasanthapuram

    Citation: Virology Journal 2008 5:64

    Content type: Research

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  14. Although the previous study demonstrated the envelope protein of dengue viruses is under purifying selection pressure, little is known about the genetic differences of full-length viral genomes of DENV-3. In o...

    Authors: Chwan-Chuen King, Day-Yu Chao, Li-Jung Chien, Gwong-Jen J Chang, Ting-Hsiang Lin, Yin-Chang Wu and Jyh-Hsiung Huang

    Citation: Virology Journal 2008 5:63

    Content type: Research

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  15. A variety of interactions between up to three different movement proteins (MPs), the coat protein (CP) and genomic DNA mediate the inter- and intra-cellular movement of geminiviruses in the genus Begomovirus. Alt...

    Authors: Eric van der Walt, Kenneth E Palmer, Darren P Martin and Edward P Rybicki

    Citation: Virology Journal 2008 5:61

    Content type: Research

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  16. HIV-1 mediated perturbation of the plasma membrane can produce an alteration in the transmembrane gradients of cations and other small molecules leading to cell death. Several HIV-1 proteins have been shown to...

    Authors: Bongkun Choi, Cesar D Fermin, Alla M Comardelle, Allyson M Haislip, Thomas G Voss and Robert F Garry

    Citation: Virology Journal 2008 5:60

    Content type: Research

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  17. The female reproductive tract is amongst the main routes for Human Immunodeficiency Virus (HIV) transmission. Cervical mucus however is known to protect the female reproductive tract from bacterial invasion an...

    Authors: Habtom H Habte, Corena de Beer, Zoë E Lotz, Marilyn G Tyler, Leann Schoeman, Delawir Kahn and Anwar S Mall

    Citation: Virology Journal 2008 5:59

    Content type: Research

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  18. The emergence of drug resistant viruses, together with the possibility of increased virulence, is an important concern in the development of new antiviral compounds. Cidofovir (CDV) is a phosphonate nucleotide...

    Authors: Marie N Becker, Maria Obraztsova, Earl R Kern, Debra C Quenelle, Kathy A Keith, Mark N Prichard, Ming Luo and Richard W Moyer

    Citation: Virology Journal 2008 5:58

    Content type: Research

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  19. We describe a novel strategy in which two inhibitors of HIV viral entry were incorporated into a single molecule. This bifunctional fusion inhibitor consists of an antibody blocking the binding of HIV to its c...

    Authors: Erhard Kopetzki, Andreas Jekle, Changhua Ji, Eileen Rao, Jun Zhang, Stephan Fischer, Nick Cammack, Surya Sankuratri and Gabrielle Heilek

    Citation: Virology Journal 2008 5:56

    Content type: Research

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  20. PTGS (post-transcriptional gene silencing) is used to counter pathogenic invasions, particularly viruses. In return, many plant viruses produce proteins which suppress silencing directed against their RNA. The...

    Authors: Christelle Siré, Martine Bangratz-Reyser, Denis Fargette and Christophe Brugidou

    Citation: Virology Journal 2008 5:55

    Content type: Research

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  21. Open reading frame 58 (ORF58) of varicella-zoster virus (VZV) lies at the 3'end of the Unique long (UL) region and its functional is unknown. In order to clarify whether ORF58 is essential for the growth of VZV, ...

    Authors: Hironori Yoshii, Kay Sadaoka, Masaaki Matsuura, Kazuhiro Nagaike, Michiaki Takahashi, Koichi Yamanishi and Yasuko Mori

    Citation: Virology Journal 2008 5:54

    Content type: Research

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  22. Foot-and-mouth disease (FMD) is endemic in Pakistan and causes huge economic losses. This work focus on the Landhi Dairy Colony (LDC), located in the suburbs of Karachi. LDC is the largest Buffalo colony in th...

    Authors: Joern Klein, Manzoor Hussain, Munir Ahmad, Muhammad Afzal and Soren Alexandersen

    Citation: Virology Journal 2008 5:53

    Content type: Research

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  23. Current methods for dengue virus quantitation are either time consuming, technically demanding or costly. As an alternative, the commercial enzyme immunoassay Platelia™ Dengue NS1 AG (Bio-Rad Laboratories) was...

    Authors: Juan E Ludert, Clemente Mosso, Ivonne Ceballos-Olvera and Rosa M del Angel

    Citation: Virology Journal 2008 5:51

    Content type: Research

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  24. Little is known about changes in hepatitis B viral load (HBV DNA) in relation to age in Africa. The aim of this study is to determine the natural course of HBV chronic infection, particularly in relation to se...

    Authors: Maimuna E Mendy, Samuel J McConkey, Marianne AB Sande van der, Sarah Crozier, Steve Kaye, David Jeffries, Andrew J Hall and Hilton C Whittle

    Citation: Virology Journal 2008 5:49

    Content type: Research

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  25. The morbidity and mortality associated with cytomegalovirus (CMV) infection in immunocompromised patients (especially in HIV-infected patients and transplant recipients), as well as with congenital CMV infecti...

    Authors: Petros I Rafailidis, Eleni G Mourtzoukou, Ioannis C Varbobitis and Matthew E Falagas

    Citation: Virology Journal 2008 5:47

    Content type: Review

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  26. Hepatitis C virus (HCV) encodes two transmembrane glycoproteins E1 and E2 which form a heterodimer. E1 is believed to mediate fusion while E2 has been shown to bind cellular receptors including CD81. In this s...

    Authors: Katharina B Rothwangl, Balaji Manicassamy, Susan L Uprichard and Lijun Rong

    Citation: Virology Journal 2008 5:46

    Content type: Research

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  27. There is overwhelming evidence that persistent infection with high-risk human papillomaviruses (HR-HPV) is the main risk factor for invasive cancer of the cervix. Due to this global public health burden, two p...

    Authors: Vandana A Govan, Edward P Rybicki and Anna-Lise Williamson

    Citation: Virology Journal 2008 5:45

    Content type: Short report

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  28. Influenza virus infection or vaccination evokes an antibody response to viral hemagglutinin (HA) and neuraminidase (NA) surface glycoproteins, which results in immunity against influenza A viruses of the same ...

    Authors: Timothy M Straight, Martin G Ottolini, Gregory A Prince and Maryna C Eichelberger

    Citation: Virology Journal 2008 5:44

    Content type: Research

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  29. Hairpin RNAs have been used to confer resistance to viruses in plants through RNA silencing. However, it has not been demonstrated that RNA silencing was effective against inoculation by aphids of non-persiste...

    Authors: Marisol Vargas, Belén Martínez-García, José Ramón Díaz-Ruíz and Francisco Tenllado

    Citation: Virology Journal 2008 5:42

    Content type: Short report

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  30. It has been demonstrated that the p53 pathway plays an important role in HIV-1 infection. Previous work from our lab has established a model demonstrating how p53 could become inactivated in HIV-1 infected cel...

    Authors: Weilin Wu, Kylene Kehn-Hall, Caitlin Pedati, Lynnsey Zweier, Iris Castro, Zachary Klase, Cynthia S Dowd, Larisa Dubrovsky, Michael Bukrinsky and Fatah Kashanchi

    Citation: Virology Journal 2008 5:41

    Content type: Research

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  31. The vaccinia virus (VV) F2L gene encodes a functional deoxyuridine triphosphatase (dUTPase) that catalyzes the conversion of dUTP to dUMP and is thought to minimize the incorporation of deoxyuridine residues i...

    Authors: Mark N Prichard, Earl R Kern, Debra C Quenelle, Kathy A Keith, Richard W Moyer and Peter C Turner

    Citation: Virology Journal 2008 5:39

    Content type: Research

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  32. Clinical diagnosis of kidney transplants related illnesses is not a simple task. Several studies were conducted to define diseases and complications after renal transplantation, but there are no comprehensive ...

    Authors: Monica Mischitelli, Anna Bellizzi, Elena Anzivino, Daniela Fioriti, Renzo Boldorini, Umberto Miglio, Fernanda Chiarini, Franco Di Monaco and Valeria Pietropaolo

    Citation: Virology Journal 2008 5:38

    Content type: Review

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  33. Intracellular influenza virus nucleoprotein (NP) is characterized by a high efficiency of homo-polymers formation, however their antigenic structure is still incompletely known. Herein, we report that RNase-re...

    Authors: Elena N Prokudina, Nataly Semenova, Valery Chumakov and Lothar Stitz

    Citation: Virology Journal 2008 5:37

    Content type: Short report

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  34. Infectious salmon anaemia (ISA) virus (ISAV), which causes ISA in marine-farmed Atlantic salmon, is an orthomyxovirus belonging to the genus Isavirus, family Orthomyxoviridae. ISAV agglutinates erythrocytes of se...

    Authors: Samuel T Workenhe, Molly JT Kibenge, Glenda M Wright, Dorota W Wadowska, David B Groman and Frederick SB Kibenge

    Citation: Virology Journal 2008 5:36

    Content type: Research

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  35. Screening wild birds for viral pathogens has become increasingly important. We tested a screening approach based on blood and cloacal and tracheal swabs collected by hunters to study the prevalence of influenz...

    Authors: Erika Lindh, Anita Huovilainen, Osmo Rätti, Christine Ek-Kommonen, Tarja Sironen, Eili Huhtamo, Hannu Pöysä, Antti Vaheri and Olli Vapalahti

    Citation: Virology Journal 2008 5:35

    Content type: Research

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  36. Since 2004, several million indigenous cases of Chikungunya virus disease occurred in Africa, the Indian Ocean, India, Asia and, recently, Europe. The virus, usually transmitted by Aedes aegypti mosquitoes, has n...

    Authors: Xavier de Lamballerie, Eric Leroy, Rémi N Charrel, Konstantin Ttsetsarkin, Stephen Higgs and Ernest A Gould

    Citation: Virology Journal 2008 5:33

    Content type: Short report

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  37. The human EED protein, a member of the superfamily of Polycomb group proteins, is involved in multiple cellular protein complexes. Its C-terminal domain, which is common to the four EED isoforms, contains seven r...

    Authors: Dina Rakotobe, Sébastien Violot, Saw See Hong, Patrice Gouet and Pierre Boulanger

    Citation: Virology Journal 2008 5:32

    Content type: Research

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  38. Chikungunya (CHIK) fever is a viral disease transmitted to humans by the bite of Chikungunya virus (CHIK virus) infected Aedes mosquitoes. CHIK virus is a member of the Alphavirus genus of the family Togaviridae....

    Authors: Sudarsanareddy Lokireddy, Sarojamma Vemula and Ramakrishna Vadde

    Citation: Virology Journal 2008 5:31

    Content type: Research

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  39. The human papillomavirus type 16 E5 protein (HPV16 E5) is 83 amino acids in length and contains three well-defined hydrophobic regions. The protein is expressed at very limited amounts in transfected cells and...

    Authors: Caroline Lewis, Marta F Baro, Margarita Marques, Myriam Grüner, Angel Alonso and Ignacio G Bravo

    Citation: Virology Journal 2008 5:30

    Content type: Research

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