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  1. A DNA mirror repeat is a sequence segment delimited on the basis of its containing a center of symmetry on a single strand, e.g. 5'-GCATGGTACG-3'. It is most frequently described in association with a function...

    Authors: Dorothy M Lang

    Citation: Virology Journal 2007 4:113

    Content type: Research

    Published on:

  2. Motavizumab (MEDI-524) is a monoclonal antibody with enhanced neutralizing activity against RSV. In mice, motavizumab suppressed RSV replication which resulted in significant reduction of clinical parameters o...

    Authors: Asunción Mejías, Susana Chávez-Bueno, Martin B Raynor, John Connolly, Peter A Kiener, Hasan S Jafri and Octavio Ramilo

    Citation: Virology Journal 2007 4:109

    Content type: Short report

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  3. The filoviruses, Ebola (EBOV) and Marburg (MARV), cause a lethal hemorrhagic fever. Human isolates of MARV are not lethal to immmunocompetent adult mice and, to date, there are no reports of a mouse-adapted MA...

    Authors: Kelly L Warfield, Derron A Alves, Steven B Bradfute, Daniel K Reed, Sean VanTongeren, Warren V Kalina, Gene G Olinger and Sina Bavari

    Citation: Virology Journal 2007 4:108

    Content type: Research

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  4. Here we investigated the nature and functional consequences of mutations in the HIV-1 tat gene within an epidemiologically-linked AIDS transmission cohort consisting of a non-progressing donor (A) and two normal ...

    Authors: Haran Sivakumaran, Bin Wang, M John Gill, Brenda Beckholdt, Nitin K Saksena and David Harrich

    Citation: Virology Journal 2007 4:107

    Content type: Short report

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  5. We have developed a system that isolates and replicates HCV in vitro. These isolates are called CIMM-HCV. This system has made it possible to analyze the biology, nature, and extent of HCV variability, among othe...

    Authors: S Zaki Salahuddin, Katherine A Snyder, Andre Godwin, Renu Grewal, John G Prichard, Ann S Kelley and Dennis Revie

    Citation: Virology Journal 2007 4:106

    Content type: Research

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  6. The nucleoprotein (NP) of Marburg virus (MARV) is responsible for the encapsidation of viral genomic RNA and the formation of the helical nucleocapsid precursors that accumulate in intracellular inclusions in ...

    Authors: Andrea DiCarlo, Peggy Möller, Angelika Lander, Larissa Kolesnikova and Stephan Becker

    Citation: Virology Journal 2007 4:105

    Content type: Research

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  7. The epidemiology of viral hepatitis during pregnancy is essential for health planners and programme managers. While much data exist concerning viral hepatitis during pregnancy in many African countries, no pro...

    Authors: Rasha M Elsheikh, Ahmed A Daak, Mohamed A Elsheikh, Mubarak S Karsany and Ishag Adam

    Citation: Virology Journal 2007 4:104

    Content type: Research

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  8. Human adenovirus serotype 5 (Ad5) has been widely explored as a gene delivery vector for a variety of diseases. Many target cells, however, express low levels of Ad5 native receptor, the Coxsackie-Adenovirus R...

    Authors: Tie Han, Yizhe Tang, Hideyo Ugai, Leslie E Perry, Gene P Siegal, Juan L Contreras and Hongju Wu

    Citation: Virology Journal 2007 4:103

    Content type: Research

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  9. Viruses that are incorporating host cell proteins might trigger autoimmune diseases. It is therefore of interest to identify possible host proteins associated with viruses, especially for enveloped viruses tha...

    Authors: Maria Hammarstedt, Jenny Ahlqvist, Steven Jacobson, Henrik Garoff and Anna Fogdell-Hahn

    Citation: Virology Journal 2007 4:101

    Content type: Research

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  10. The human immunodeficiency virus type 1 (HIV-1) has been intensely investigated since its discovery in 1983 as the cause of acquired immune deficiency syndrome (AIDS). With relatively few proteins made by the ...

    Authors: Joshua M Costin

    Citation: Virology Journal 2007 4:100

    Content type: Review

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  11. The adeno-associated virus (AAV) has rapidly gained popularity in gene therapy since the establishment of the first AAV2 infectious clone, in 1982, due to some of their distinguishing characteristics such as l...

    Authors: Renata dosSantos Coura and Nance Beyer Nardi

    Citation: Virology Journal 2007 4:99

    Content type: Review

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    The Erratum to this article has been published in Virology Journal 2010 7:12

  12. Genotype 4 hepatitis E virus (HEV) was reportedly transmitted freely between humans and swine in eastern China. The full-length genomic sequence of Shanghai swine isolate (SH-SW-zs1) recovered from feces sampl...

    Authors: Quan Shen, Wen Zhang, Xiangrong Cao, Jing Mou, Li Cui and Xiuguo Hua

    Citation: Virology Journal 2007 4:98

    Content type: Research

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  13. The recently sequenced 218 kb genome of morphologically atypical Bacillus thuringiensis phage 0305φ8-36 exhibited only limited detectable homology to known bacteriophages. The only known relative of this phage is...

    Authors: Stephen C Hardies, Julie A Thomas and Philip Serwer

    Citation: Virology Journal 2007 4:97

    Content type: Research

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  14. Rabbit Hemorrhagic Disease (RHD) is a severe acute viral disease specifically affecting the European rabbit Oryctolagus cuniculus. As the European rabbit is the predominant species of domestic rabbit throughout t...

    Authors: Michael T McIntosh, Shawn C Behan, Fawzi M Mohamed, Zhiqiang Lu, Karen E Moran, Thomas G Burrage, John G Neilan, Gordon B Ward, Giuliana Botti, Lorenzo Capucci and Samia A Metwally

    Citation: Virology Journal 2007 4:96

    Content type: Research

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  15. Natural multiple viral infections of cultivated cowpeas have been reported in Nigeria. In this study, three Nigerian commercial cowpea cultivars ("Olo 11", "Oloyin" and "White") and two lines from the IITA (IT...

    Authors: Moni A Taiwo, Kehinde T Kareem, Imade Y Nsa and Jackies D'A Hughes

    Citation: Virology Journal 2007 4:95

    Content type: Research

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  16. Myxoma virus (MYXV), a leporide-specific poxvirus, represents an attractive candidate for the generation of safe, non-replicative vaccine vector for non-host species. However, there is very little information ...

    Authors: Béatrice Pignolet, Jean-Luc Duteyrat, Aude Allemandou, Jacqueline Gelfi, Gilles Foucras and Stéphane Bertagnoli

    Citation: Virology Journal 2007 4:94

    Content type: Short report

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  17. Hepatitis B virus (HBV) infection is a serious health problem worldwide. Treatment recommendation and response are mainly indicated by viral load, e antigen (HBeAg) seroconversion, and ALT levels. The S antige...

    Authors: Min Lian, Xu Zhou, Lai Wei, Shihong Qiu, Tong Zhou, Lanfen Li, Xiaocheng Gu, Ming Luo and Xiaofeng Zheng

    Citation: Virology Journal 2007 4:93

    Content type: Methodology

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  18. The highly heterogenic characteristic of viruses is the major obstacle to efficient DNA amplification. Taking advantage of the large number of virus DNA sequences in public databases to select conserved sites ...

    Authors: Qingrun Zhang, Guanghua Wu, Elliott Richards, Shan'gang Jia and Changqing Zeng

    Citation: Virology Journal 2007 4:92

    Content type: Methodology

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    The Retraction Note to this article has been published in Virology Journal 2007 4:119

  19. Dengue and Dengue hemorrhagic fever have emerged as some of the most important mosquito-borne viral diseases in the tropics. The mechanisms of pathogenesis of Dengue remain elusive. Recently, virus-induced apo...

    Authors: Indira Umareddy, Olivier Pluquet, Qing Yin Wang, Subhash G Vasudevan, Eric Chevet and Feng Gu

    Citation: Virology Journal 2007 4:91

    Content type: Research

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  20. The genetic characterization of wild-type measles strains isolated during an epidemic cluster of measles occurred in Puglia (South Italy), between November 2006 and January 2007, was performed. Measles virus (...

    Authors: Maria Chironna, Rosa Prato, Anna Sallustio, Domenico Martinelli, Cinzia Germinario, Pierluigi Lopalco and Michele Quarto

    Citation: Virology Journal 2007 4:90

    Content type: Short report

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  21. Alpha interferon in combination with ribavirin is the standard therapy for hepatitis C virus infection. Unfortunately, a significant number of patients fail to eradicate their infection with this regimen. The ...

    Authors: Sidhartha Hazari, Lizeth Taylor, Salima Haque, Robert F Garry, Sander Florman, Ronald Luftig, Frederic Regenstein and Srikanta Dash

    Citation: Virology Journal 2007 4:89

    Content type: Research

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  22. Endothelial cells are a target for gene therapy because they are implicated in a number of vascular diseases. Recombinant baculovirus have emerged as novel gene delivery vectors. However, there is no informati...

    Authors: Agustín Luz-Madrigal, Carmen Clapp, Jorge Aranda and Luis Vaca

    Citation: Virology Journal 2007 4:88

    Content type: Research

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  23. Kaposi's sarcoma associated herpesvirus (KSHV) is the etiologic agent of Kaposi's sarcoma (KS), a highly vascularized neoplasm characterized by endothelial-derived spindle-shaped tumor cells. KSHV-infected mic...

    Authors: Bryan D Shelby, Heather L LaMarca, Harris E McFerrin, Anne B Nelson, Joseph A Lasky, Gang Sun, Leslie Myatt, Margaret K Offermann, Cindy A Morris and Deborah E Sullivan

    Citation: Virology Journal 2007 4:87

    Content type: Research

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  24. Noroviruses are the most common cause of non-bacterial gastroenteritis. Improved detection methods have seen a large increase in the number of human NoV genotypes in the last ten years. The objective of this s...

    Authors: John F Menton, Karen Kearney and John G Morgan

    Citation: Virology Journal 2007 4:86

    Content type: Research

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  25. HTLV-I infected CD4+ T-cells lines usually progress towards a CD3- or CD3low phenotype. In this paper, we studied expression, kinetics, chromatin remodeling of the CD3 gene at different time-points post HTLV-I in...

    Authors: Haidar Akl, Bassam Badran, Gratiela Dobirta, Germain Manfouo-Foutsop, Maria Moschitta, Makram Merimi, Arsène Burny, Philippe Martiat and Karen E Willard-Gallo

    Citation: Virology Journal 2007 4:85

    Content type: Research

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  26. Targeting the highly conserved herpes DNA polymerase (DPOL) gene with PCR using panherpes degenerate primers is a powerful tool to universally detect unknown herpesviruses. However, vertebrate hosts are often ...

    Authors: Sandra Prepens, Karl-Anton Kreuzer, Fabian Leendertz, Andreas Nitsche and Bernhard Ehlers

    Citation: Virology Journal 2007 4:84

    Content type: Methodology

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  27. Japanese encephalitis virus (JEV) is a member of mosquito-borne Flaviviridae. To date, the mechanisms of the early events of JEV infection remain poorly understood, and the cellular receptors are unidentified. Th...

    Authors: Junping Ren, Tianbing Ding, Wei Zhang, Jianhua Song and Wenyu Ma

    Citation: Virology Journal 2007 4:83

    Content type: Hypothesis

    Published on:

  28. Lymphocytes provide invaluable whistle blowers of changes due to infections. We use the information registered by these cells using their mRNAs as they encounter the pathogen to develop patterns of expression ...

    Authors: Rasha Hammamieh, Mohsen Barmada, George Ludwig, Sheila Peel, Nick Koterski and Marti Jett

    Citation: Virology Journal 2007 4:82

    Content type: Research

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  29. The human immunodeficiency virus type 1(HIV-1) is a complex retrovirus and the causative agent of acquired immunodeficiency syndrome (AIDS). The HIV-1 Vpu protein is an oligomeric integral membrane protein ess...

    Authors: Amjad Hussain, Suman R Das, Charu Tanwar and Shahid Jameel

    Citation: Virology Journal 2007 4:81

    Content type: Research

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  30. Thottapalayam (TPM) virus belongs to the genus Hantavirus, family Bunyaviridae. The genomes of hantaviruses consist of three negative-stranded RNA segments (S, M and L) encoding the virus nucleocapsid (N), glycop...

    Authors: Pragya D Yadav, Martin J Vincent and Stuart T Nichol

    Citation: Virology Journal 2007 4:80

    Content type: Short report

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  31. Hepatitis C virus (HCV) has been the subject of intense research and clinical investigation as its major role in human disease has emerged. Previous and recent studies have suggested a diversification of type ...

    Authors: Gonzalo Moratorio, Mariela Martínez, María F Gutiérrez, Katiuska González, Rodney Colina, Fernando López-Tort, Lilia López, Ricardo Recarey, Alejandro G Schijman, María P Moreno, Laura García-Aguirre, Aura R Manascero and Juan Cristina

    Citation: Virology Journal 2007 4:79

    Content type: Research

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  32. In 2005 huge epizooty of H5N1 HPAI occurred in Russia. It had been clear that territory of Russia becoming endemic for H5N1 HPAI. In 2006 several outbreaks have occurred. To develop new vaccines and antiviral ...

    Authors: Vasily A Evseenko, Eugeny K Bukin, Anna V Zaykovskaya, Kirill A Sharshov, Vladimir A Ternovoi, George M Ignatyev and Alexander M Shestopalov

    Citation: Virology Journal 2007 4:77

    Content type: Research

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  33. Profilins are critical to cytoskeletal dynamics in eukaryotes; however, little is known about their viral counterparts. In this study, a poxviral profilin homolog, ectromelia virus strain Moscow gene 141 (ECTV...

    Authors: Christine Butler-Cole, Mary J Wagner, Melissa Da Silva, Gordon D Brown, Robert D Burke and Chris Upton

    Citation: Virology Journal 2007 4:76

    Content type: Research

    Published on:

  34. The Sydney blood bank cohort (SBBC) of long-term survivors consists of multiple individuals infected with attenuated, nef-deleted variants of human immunodeficiency virus type 1 (HIV-1) acquired from a single sou...

    Authors: Lachlan Gray, Melissa J Churchill, Jasminka Sterjovski, Kristie Witlox, Jennifer C Learmont, John S Sullivan, Steven L Wesselingh, Dana Gabuzda, Anthony L Cunningham, Dale A McPhee and Paul R Gorry

    Citation: Virology Journal 2007 4:75

    Content type: Research

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  35. There are eight genotypes of hepatitis B virus (A-H) and subgenotypes are recognized. Genotyping can be accomplished based on a partial sequence of HBV genome such as the pre-S or S gene. Several methods have ...

    Authors: Abdel-Rahman N Zekri, Mohamed M Hafez, Nahed I Mohamed, Zeinab K Hassan, Manal H El-Sayed, Mohsen M Khaled and Tarek Mansour

    Citation: Virology Journal 2007 4:74

    Content type: Research

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  36. To elucidate the relationship between resistance to HRSV neutralizing antibodies directed against the F protein and the fusion activity of the F protein, a recombinant approach was used to generate a panel of ...

    Authors: Changbao Liu, Nicole D Day, Patrick J Branigan, Lester L Gutshall, Robert T Sarisky and Alfred M Del Vecchio

    Citation: Virology Journal 2007 4:71

    Content type: Short report

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  37. The binding of viral-specific antibodies to cell-surface antigens usually results in down modulation of the antigen through redistribution of antigens into patches that subsequently may be internalized by endo...

    Authors: Rosa E Sarmiento, Rocio G Tirado, Laura E Valverde and Beatriz Gómez-Garcia

    Citation: Virology Journal 2007 4:68

    Content type: Research

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  38. Two recombinant, live attenuated human parainfluenza virus type 1 (rHPIV1) mutant viruses have been developed, using a reverse genetics system, for evaluation as potential intranasal vaccine candidates. These ...

    Authors: Emmalene J Bartlett, Adam Castaño, Sonja R Surman, Peter L Collins, Mario H Skiadopoulos and Brian R Murphy

    Citation: Virology Journal 2007 4:67

    Content type: Research

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  39. HTLV-1 Gag protein is a matrix protein that contains the PTAP and PPPY sequences as L-domain motifs and which can be released from mammalian cells in the form of virus-like particles (VLPs). The cellular facto...

    Authors: Shuzo Urata, Hideyoshi Yokosawa and Jiro Yasuda

    Citation: Virology Journal 2007 4:66

    Content type: Research

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  40. PCR-based detection and identification of viruses assumes a known, relatively stable genome. Unfortunately, high mutation rates may lead to extensive changes in viral nucleic acid sequences making dedicated PC...

    Authors: Amy L Clem, Jonathan Sims, Sucheta Telang, John W Eaton and Jason Chesney

    Citation: Virology Journal 2007 4:65

    Content type: Research

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  41. Lysogenic mode of life cycle of a temperate bacteriophage is generally maintained by a protein called 'repressor'. Repressor proteins of temperate lambdoid phages bind to a few symmetric operator DNAs in order...

    Authors: Tridib Ganguly, Amitava Bandhu, Partho Chattoraj, Palas K Chanda, Malabika Das, Nitai C Mandal and Subrata Sau

    Citation: Virology Journal 2007 4:64

    Content type: Research

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  42. The epidemiological significance of Hepatitis B virus genotypes has been well established and becoming an essential concern day by day however, much little is known about the mixed infection with more than one...

    Authors: Muhammad Masroor Alam, Sohail Zahoor Zaidi, Shehzad Shaukat, Salmaan Sharif, Mehar Angez, Asif Naeem, Shamim Saleha, Javed Aslam Butt and Salman Akbar Malik

    Citation: Virology Journal 2007 4:63

    Content type: Research

    Published on: