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23 result(s) for 'chloroquine an inhibitor of SARS' within Virology Journal

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  1. Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available.

    Authors: Martin J Vincent, Eric Bergeron, Suzanne Benjannet, Bobbie R Erickson, Pierre E Rollin, Thomas G Ksiazek, Nabil G Seidah and Stuart T Nichol
    Citation: Virology Journal 2005 2:69
  2. Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2 and broke out as a global pandemic in late 2019. The acidic pH environment of endosomes is believed to be essential for SARS-CoV-2 to be able to enter ....

    Authors: Chao Shang, Xinyu Zhuang, He Zhang, Yiquan Li, Yilong Zhu, Jing Lu, Chenchen Ge, Jianan Cong, Tingyu Li, Mingyao Tian, Ningyi Jin and Xiao Li
    Citation: Virology Journal 2021 18:46
  3. Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection has spread rapidly across the world and become an international public health emergency. Both SARS-CoV-2 and SARS-CoV belong to subfamily Coronav...

    Authors: Yicheng Yang, Zhiqiang Xiao, Kaiyan Ye, Xiaoen He, Bo Sun, Zhiran Qin, Jianghai Yu, Jinxiu Yao, Qinghua Wu, Zhang Bao and Wei Zhao
    Citation: Virology Journal 2020 17:117
  4. The coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to plague the world. While COVID-19 is asymptomatic in most individuals, it can caus...

    Authors: Yunes Panahi, Armita Mahdavi Gorabi, Sona Talaei, Fatemeh Beiraghdar, Abolfazl Akbarzadeh, Vahideh Tarhriz and Hassan Mellatyar
    Citation: Virology Journal 2023 20:23
  5. The ongoing coronavirus disease 2019 (COVID-19) pandemic constitutes a serious public health concern worldwide. Currently, more than 6 million deaths have occurred despite drastic containment measures, and thi...

    Authors: Tianjiao Shan, Lan-ya Li, Jin-Ming Yang and Yan Cheng
    Citation: Virology Journal 2023 20:125
  6. Chloroquine is a 4-aminoquinoline previously used in malaria therapy and now becoming an emerging investigational antiviral drug due to its broad spectrum of antiviral activities. To explore whether the low pH...

    Authors: Livia Di Trani, Andrea Savarino, Laura Campitelli, Sandro Norelli, Simona Puzelli, Daniela D'Ostilio, Edoardo Vignolo, Isabella Donatelli and Antonio Cassone
    Citation: Virology Journal 2007 4:39
  7. Coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2, previously named 2019-nCov), a novel coronavirus that emerged in China in December 2019 and was dec...

    Authors: Sumanth Khadke, Nayla Ahmed, Nausheen Ahmed, Ryan Ratts, Shine Raju, Molly Gallogly, Marcos de Lima and Muhammad Rizwan Sohail
    Citation: Virology Journal 2020 17:154
  8. Coronavirus disease 19 (COVID-19) is the disease caused by SARS-CoV-2, a highly infectious member of the coronavirus family, which emerged in December 2019 in “Wuhan, China”. It induces respiratory illness ran...

    Authors: Sawsan Aboul-Fotouh, Ahmed Nageh Mahmoud, Esraa M. Elnahas, Mohamed Z. Habib and Sahar M. Abdelraouf
    Citation: Virology Journal 2023 20:241
  9. Beginning in late 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged as a novel pathogen that causes coronavirus disease 2019 (COVID-19). SARS-CoV-2 has infected more than 111 mi...

    Authors: Zachary A. Krumm, Grace M. Lloyd, Connor P. Francis, Lith H. Nasif, Duane A. Mitchell, Todd E. Golde, Benoit I. Giasson and Yuxing Xia
    Citation: Virology Journal 2021 18:66
  10. The recent outbreak of the Coronavirus pandemic resulted in a successful vaccination program launched by the World Health Organization. However, a large population is still unvaccinated, leading to the emergen...

    Authors: Samar Sami Alkafaas, Abanoub Mosaad Abdallah, Aya Misbah Hussien, Heba Bedair, Mahmoud Abdo, Soumya Ghosh, Sara Samy Elkafas, Wilgince Apollon, Morteza Saki, Samah A. Loutfy, Helen Onyeaka and Mohamed Hessien
    Citation: Virology Journal 2023 20:191
  11. Since December 2019, various types of strategies have been applied due to the emergent need to investigate the biology and pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to discov...

    Authors: Mohadese Hashem Boroojerdi, Tariq Al Jabry, Seyed Mohamad Javad Mirarefin and Halima Albalushi
    Citation: Virology Journal 2023 20:37
  12. Coronavirus disease 2019 is a global pandemic caused by SARS-CoV-2. The emergence of its variant strains has posed a considerable challenge to clinical treatment. Therefore, drugs capable of inhibiting SARS-Co...

    Authors: Cuiling Zhang, Bingjie Wei, Zirui Liu, Wei Yao, Yiquan Li, Jing Lu, Chenchen Ge, Xiaoyang Yu, Dapeng Li, Yilong Zhu, Chao Shang, Ningyi Jin and Xiao Li
    Citation: Virology Journal 2023 20:18
  13. The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a global health emergency (COVID-19) because of its rapid spread and high mortality. Since the virus epidemic, ...

    Authors: Wenjing Gu, Hui Gan, Yu Ma, Lina Xu, Zhangkai J. Cheng, Bizhou Li, Xinxing Zhang, Wujun Jiang, Jinlv Sun, Baoqing Sun and Chuangli Hao
    Citation: Virology Journal 2022 19:49
  14. The rise of the highly lethal severe acute respiratory syndrome-2 (SARS-2) as corona virus 2019 (COVID-19) reminded us of the history of other pandemics that happened in the last century (Spanish flu) and stay...

    Authors: Walid F. Elkhatib, Shereen S. Abdelkareem, Wafaa S. Khalaf, Mona I. Shahin, Dounia Elfadil, Alaa Alhazmi, Ahmed I. El-Batal and Gharieb S. El-Sayyad
    Citation: Virology Journal 2022 19:167
  15. The international SARS-CoV-2 pandemic has resulted in an urgent need to identify new anti-viral drugs for treatment of COVID-19. The initial step to identifying potential candidates usually involves in vitro s...

    Authors: Kexin Yan, Daniel J. Rawle, Thuy T. Le and Andreas Suhrbier
    Citation: Virology Journal 2021 18:123
  16. The aim of this study was to evaluate the role of antiviral drugs in reducing the risk of developing severe illness in patients with moderate COVID-19 pneumonia.

    Authors: Peng Yin, Juan Meng, Jincheng Chen, Junxiao Gao, Dongqi Wang, Shuyan Liu, Qinglong Guo, Muchun Zhu, Gengwei Zhang, Yingxia Liu, Ye Li and Guoliang Zhang
    Citation: Virology Journal 2021 18:142
  17. Since its outbreak in 2019, the coronavirus disease (COVID-19) has become a pandemic, affecting more than 52 million people and causing more than 1 million mortalities globally till date. Current research reve...

    Authors: Baila Shakaib, Tanzeel Zohra, Aamer Ikram, Muhammad Bin Shakaib, Amna Ali, Adnan Bashir, Muhammad Salman, Mumtaz Ali khan and Jamil Ansari
    Citation: Virology Journal 2021 18:120
  18. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has spread to many countries around the world. In addition to lung disease, severe cases also displayed varying degrees of liver injury. This articl...

    Authors: Dongdong Yu, Qingru Du, Shengguang Yan, Xu-Guang Guo, Yehao He, Guodong Zhu, Kewei Zhao and Shi Ouyang
    Citation: Virology Journal 2021 18:121
  19. After the first reporting of the index case of Severe Acute Respiratory Syndrome (SARS)-CoV-2-associated disease at the end of December 2019, the virus spread quickly throughout the world, prompting the WHO on...

    Authors: Zahra Hamidi, Shaghaiegh Jabraeili-Siahroud, Yalda Taati-Alamdari, Parisa Shiri Aghbash, Ali Shamekh and Hossein Bannazadeh Baghi
    Citation: Virology Journal 2023 20:1
  20. Foamy viruses (FVs) are retroviruses with unique replication strategies that cause lifelong latent infections in their hosts. FVs can also produce foam-like cytopathic effects in vitro. However, the effect of ...

    Authors: Zhaohuan Wang, Xiaopeng Tuo, Junshi Zhang, Keli Chai, Juan Tan and Wentao Qiao
    Citation: Virology Journal 2022 19:195
  21. Porcine epidemic diarrhea virus (PEDV) of the family Coronaviridae has caused substantial economic losses in the swine husbandry industry. There’s currently no specific drug available for treatment of coronavirus...

    Authors: Cui-Cui Li and Xiao-Jia Wang
    Citation: Virology Journal 2020 17:71