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Positive-strand RNA viruses

Section Editor: Alexander A Khromykh, University of Queensland, Australia
Deputy Section Editor: Michael Beard, University of Adelaide, Australia

The Positive-strand RNA viruses section of Virology Journal invites submissions of research articles and reviews covering all aspects of positive-strand RNA virus biology. Basic research topics of interest include all facets of the viral life cycle from viral attachment and entry, viral RNA replication and translation, viral gene expression/regulation, viral protein processing, viral particle assembly and secretion. We welcome studies that investigate interactions between the virus and host that impact viral replication and the cellular response to infection. Other topics include but are not limited to viral pathogenesis, epidemiology, and viral immunology. We also welcome basic and translational studies on the development of novel model systems, antiviral drugs and vaccines.

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  1. In recent decades, Echovirus 30 (E30) and Japanese encephalitis virus (JEV) have been reported to be the common causative agents of acute meningitis among patients in South East Asia. An E30 outbreak in Vietna...

    Authors: Yuki Takamatsu, Leo Uchida, Phan Thi Nga, Kenta Okamoto, Takeshi Nabeshima, Dang Thi Thu Thao, Do Thien Hai, Nguyen Thi Tuyet, Hoang Minh Duc, Le Xuan Luat, Futoshi Hasebe and Kouichi Morita

    Citation: Virology Journal 2013 10:280

    Content type: Case Report

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  2. Chikungunya virus (CHIKV) is an alphavirus of the Togaviridae family. After autoproteolytic cleavage, the CHIKV capsid protein (CP) is involved in RNA binding and assembly of the viral particle. The monomeric CP ...

    Authors: Saijo Thomas, Jagdish Rai, Lijo John, Stephan Schaefer, Brigitte M Pützer and Ottmar Herchenröder

    Citation: Virology Journal 2013 10:269

    Content type: Research

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  3. The clinical presentation of dengue is classified by the World Health Organization into dengue without warning signs, dengue with warning signs and severe dengue. Reports of neurological disease caused by Dengue ...

    Authors: Kátia Paulino Ribeiro de Souza, Emanuele Guimarães Silva, Eliseu Soares de Oliveira Rocha, Leandra Barcelos Figueiredo, Camila Megale de Almeida-Leite, Rosa Maria Esteves Arantes, Juliana de Assis Silva Gomes, Gustavo Portela Ferreira, Jaquelline Germano de Oliveira, Erna Geessien Kroon and Marco Antônio Campos

    Citation: Virology Journal 2013 10:267

    Content type: Research

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  4. Evaluation of the primary etiologic agents that cause aseptic meningitis outbreaks may provide valuable information regarding the prevention and management of aseptic meningitis. An outbreak of aseptic meningi...

    Authors: Hong Xiao, Dawei Guan, Ruiyu Chen, Pingxi Chen, Corina Monagin, Wei Li, Juan Su, Cong Ma, Wanli Zhang and Changwen Ke

    Citation: Virology Journal 2013 10:263

    Content type: Research

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  5. Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus that causes acute viral encephalitis in humans. Pigs are important amplifiers of JEV. The entry mechanism of JEV into porcine cells remains larg...

    Authors: Songbai Yang, Minhui He, Xiangdong Liu, Xinyun Li, Bin Fan and Shuhong Zhao

    Citation: Virology Journal 2013 10:258

    Content type: Research

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  6. Several studies have shown that American genotype dengue 2 viruses (DENV2) have reduced viral fitness in the mosquito vector, Aedes aegypti, compared to other DENV2 genotypes. Diminished replication efficiency or...

    Authors: Cynthia CH Khoo, Jeffrey B Doty, Nicole L Held, Ken E Olson and Alexander WE Franz

    Citation: Virology Journal 2013 10:257

    Content type: Research

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  7. Ophiostoma novo-ulmi is the causative agent of Dutch elm disease (DED). It is an ascomycetous filamentous fungus that ranks as the third most devastating fungal pathogen in Canada. The disease front has spread ea...

    Authors: William E Hintz, Joyce S Carneiro, Irina Kassatenko, Aniko Varga and Delano James

    Citation: Virology Journal 2013 10:252

    Content type: Research

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  8. The flaviviral nonstructural protein 5 (NS5) is a phosphoprotein, though the precise identities and roles of many specific phosphorylations remain unknown. Protein kinase G (PKG), a cGMP-dependent protein kina...

    Authors: Julie A Keating, Dipankar Bhattacharya, Pei-Yin Lim, Shaun Falk, Bernard Weisblum, Kristen A Bernard, Mayuri Sharma, Richard J Kuhn and Rob Striker

    Citation: Virology Journal 2013 10:242

    Content type: Research

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  9. Chikungunya virus (CHIKV) has been responsible for large epidemic outbreaks causing fever, headache, rash and severe arthralgia. So far, no specific treatment or vaccine is available. As nucleic acid amplifica...

    Authors: Sabine Gläsker, Aleksei Lulla, Valeria Lulla, Therese Couderc, Jan Felix Drexler, Peter Liljeström, Marc Lecuit, Christian Drosten, Andres Merits and Beate Mareike Kümmerer

    Citation: Virology Journal 2013 10:235

    Content type: Methodology

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  10. Cryopreserved primary human renal proximal tubule epithelial cells (RPTEC) were obtained from a commercial supplier for studies of Simian virus 40 (SV40). Within twelve hrs after cell cultures were initiated, cyt...

    Authors: John A Lednicky, Thomas B Waltzek, Elizabeth McGeehan, Julia C Loeb, Sara B Hamilton and Maya C Luetke

    Citation: Virology Journal 2013 10:213

    Content type: Research

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