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Positive-strand RNA viruses

Section Editor: Alexander A Khromykh, University of Queensland, Australia
Deputy Section Editor: Michael Beard, University of Adelaide, Australia

The Positive-strand RNA viruses section of Virology Journal invites submissions of research articles and reviews covering all aspects of positive-strand RNA virus biology. Basic research topics of interest include all facets of the viral life cycle from viral attachment and entry, viral RNA replication and translation, viral gene expression/regulation, viral protein processing, viral particle assembly and secretion. We welcome studies that investigate interactions between the virus and host that impact viral replication and the cellular response to infection. Other topics include but are not limited to viral pathogenesis, epidemiology, and viral immunology. We also welcome basic and translational studies on the development of novel model systems, antiviral drugs and vaccines.

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  1. Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus that causes acute viral encephalitis in humans. Pigs are important amplifiers of JEV. The entry mechanism of JEV into porcine cells remains larg...

    Authors: Songbai Yang, Minhui He, Xiangdong Liu, Xinyun Li, Bin Fan and Shuhong Zhao

    Citation: Virology Journal 2013 10:258

    Content type: Research

    Published on:

  2. Several studies have shown that American genotype dengue 2 viruses (DENV2) have reduced viral fitness in the mosquito vector, Aedes aegypti, compared to other DENV2 genotypes. Diminished replication efficiency or...

    Authors: Cynthia CH Khoo, Jeffrey B Doty, Nicole L Held, Ken E Olson and Alexander WE Franz

    Citation: Virology Journal 2013 10:257

    Content type: Research

    Published on:

  3. Ophiostoma novo-ulmi is the causative agent of Dutch elm disease (DED). It is an ascomycetous filamentous fungus that ranks as the third most devastating fungal pathogen in Canada. The disease front has spread ea...

    Authors: William E Hintz, Joyce S Carneiro, Irina Kassatenko, Aniko Varga and Delano James

    Citation: Virology Journal 2013 10:252

    Content type: Research

    Published on:

  4. The flaviviral nonstructural protein 5 (NS5) is a phosphoprotein, though the precise identities and roles of many specific phosphorylations remain unknown. Protein kinase G (PKG), a cGMP-dependent protein kina...

    Authors: Julie A Keating, Dipankar Bhattacharya, Pei-Yin Lim, Shaun Falk, Bernard Weisblum, Kristen A Bernard, Mayuri Sharma, Richard J Kuhn and Rob Striker

    Citation: Virology Journal 2013 10:242

    Content type: Research

    Published on:

  5. Chikungunya virus (CHIKV) has been responsible for large epidemic outbreaks causing fever, headache, rash and severe arthralgia. So far, no specific treatment or vaccine is available. As nucleic acid amplifica...

    Authors: Sabine Gläsker, Aleksei Lulla, Valeria Lulla, Therese Couderc, Jan Felix Drexler, Peter Liljeström, Marc Lecuit, Christian Drosten, Andres Merits and Beate Mareike Kümmerer

    Citation: Virology Journal 2013 10:235

    Content type: Methodology

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  6. Cryopreserved primary human renal proximal tubule epithelial cells (RPTEC) were obtained from a commercial supplier for studies of Simian virus 40 (SV40). Within twelve hrs after cell cultures were initiated, cyt...

    Authors: John A Lednicky, Thomas B Waltzek, Elizabeth McGeehan, Julia C Loeb, Sara B Hamilton and Maya C Luetke

    Citation: Virology Journal 2013 10:213

    Content type: Research

    Published on: