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Herpes viruses

Section Editor: Blossom Damania, University of North Carolina at Chapel Hill, USA​​​​​​​ 
Deputy Section Editor: Anthony Nicola, Washington State University, USA​​​​​​​

The Herpes viruses section of Virology Journal includes research articles and reviews on both human and animal herpes viruses. This includes basic, mechanistic, and translational studies of herpes virus biology and pathogenesis. Topics include, but are not limited to, virus biology, virus entry, virus-host interactions, viral pathogenesis, viral cancers, antivirals and vaccines.

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  1. Epstein-Barr virus (EBV) is associated with 20-40% of Hodgkin’s Lymphoma (HL) cases. EBV-encoded latent membrane protein 1 (LMP1) is a well-known oncogenic protein and two C-terminal deletion variants, del30-L...

    Authors: Charlotte Sueur, Julien Lupo, Philippe Mas, Patrice Morand and Véronique Boyer
    Citation: Virology Journal 2014 11:94
  2. Since the type of herpes simplex virus (HSV) infection affects prognosis and subsequent counseling, type-specific testing to distinguish HSV-1 from HSV-2 is always recommended. Although PCR has been the diagno...

    Authors: Jérôme LeGoff, Hélène Péré and Laurent Bélec
    Citation: Virology Journal 2014 11:83

    The Erratum to this article has been published in Virology Journal 2015 12:167

  3. Murine cytomegalovirus (MCMV) is increasingly used as an infectious model to investigate host-pathogen interactions in mice. Detailed methods have been published for using primary murine embryonic fibroblasts ...

    Authors: Katherine A Zurbach, Toktam Moghbeli and Christopher M Snyder
    Citation: Virology Journal 2014 11:71
  4. Herpesviruses are ubiquitous pathogens that infect and cause recurrent disease in multiple animal species. Feline herpesvirus-1 (FHV-1), a member of the alphaherpesvirus family, causes respiratory illness and ...

    Authors: Samantha L Semenkow, Nicole M Johnson, David J Maggs and Barry J Margulies
    Citation: Virology Journal 2014 11:34
  5. Epstein-Barr Virus (EBV) latently infects ~10% of gastric carcinomas (GC). Epstein-Barr Nuclear Antigen 1 (EBNA1) is expressed in EBV-associated GC, and can bind host DNA, where it may impact cellular gene reg...

    Authors: Fang Lu, Italo Tempera, Hyunna T Lee, Karen DeWispelaere and Paul M Lieberman
    Citation: Virology Journal 2014 11:12
  6. HCMV encodes a stable 5 kb RNA of unknown function that is conserved across cytomegalovirus species. In vivo studies of the MCMV orthologue, a 7.2 kb RNA, demonstrated that viruses that do not express the RNA fai...

    Authors: Toni M Schwarz, Lysa-Anne M Volpe, Christopher G Abraham and Caroline A Kulesza
    Citation: Virology Journal 2013 10:348
  7. Herpes simplex virus type-1(HSV-1) and HSV-2 are important human pathogens that cause significant ocular and urogenital complications, respectively. We have previously shown that HSV-1 virions lacking glycopro...

    Authors: Arun V Iyer, Bapi Pahar, Vladimir N Chouljenko, Jason D Walker, Brent Stanfield and Konstantin G Kousoulas
    Citation: Virology Journal 2013 10:317
  8. Epstein-Barr virus (EBV) is an etiological cause of many human lymphocytic and epithelial malignancies. EBV expresses different genes that are associated with three latency types. To date, as many as 44 EBV-en...

    Authors: Hong-Jie Yang, Tie-Jun Huang, Chang-Fu Yang, Li-Xia Peng, Ran-Yi Liu, Guang-Da Yang, Qiao-Qiao Chu, Jia-Ling Huang, Na Liu, Hong-Bing Huang, Zhen-Yu Zhu, Chao-Nan Qian and Bi-Jun Huang
    Citation: Virology Journal 2013 10:314
  9. Varicella zoster virus (VZV) is a neurotropic alphaherpesvirus that infects humans and results in chickenpox and herpes zoster. A number of VZV genes remain functionally uncharacterized and since VZV is an obl...

    Authors: Christine Meyer, Jesse Dewane, Kristen Haberthur, Flora Engelmann, Nicole Arnold, Wayne Gray and Ilhem Messaoudi
    Citation: Virology Journal 2013 10:278
  10. Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related mortality worldwide, and novel treatment modalities to improve the prognosis of patients with advanced disease are highly desirable. On...

    Authors: Jhy-Ming Li, Kuo-Chin Kao, Li-Fu Li, Tsung-Ming Yang, Chean-Ping Wu, Yan-Ming Horng, William WG Jia and Cheng-Ta Yang
    Citation: Virology Journal 2013 10:241
  11. The MCMV major immediate early promoter/enhancer (MIEP) is a bidirectional promoter that drives the expression of the three immediate early viral genes, namely ie1, ie2 and ie3. The regulation of their express...

    Authors: Franziska Dag, Adrien Weingärtner, Milada Butueva, Ianina Conte, Julia Holzki, Tobias May, Barbara Adler, Dagmar Wirth and Luka Cicin-Sain
    Citation: Virology Journal 2013 10:197
  12. Most viruses take advantage of endocytic pathways to gain entry into host cells and initiate infections. Understanding of virus entry via endocytosis is critically important for the design of antiviral strateg...

    Authors: Eric Barrow, Anthony V Nicola and Jin Liu
    Citation: Virology Journal 2013 10:177
  13. A severe MD was broken out at a farm in Shandong, China, despite FC126 vaccination of the chickens at 1-day-old. The mortality of the flocks reached up to 38.3%. The infected chickens were found to have MD pat...

    Authors: Zhenhua Gong, Lijuan Zhang, Jianlin Wang, Linlin Chen, Hu Shan, Zhiliang Wang and Hongchao Ma
    Citation: Virology Journal 2013 10:155