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Fig. 2 | Virology Journal

Fig. 2

From: Ultrastructural study confirms the formation of single and heterotypic syncytial cells in bronchoalveolar fluids of COVID-19 patients

Fig. 2

Syncytial cells of neutrophils origin showed the plasma membrane fusion initiation. (A) PAP imaging of syncytia with the dense nucleus and granular cytoplasm confirming the neutrophil origin. (B) Neutrophil origin syncytial cell with multiple nuclei and immunofluorescence confirming SARS-CoV-2 infection C. SEM image of neutrophil origin syncytial cell of size 40 μm. The rough surface with plasma membrane protrusions with plenty of virus-like particles (white arrow) confirmed the neutrophil origin. (D, E & F) low and high magnification TEM images showing initiation of syncytia formation (membrane fusion). N, nucleus; M, mitochondria; P, phagosomes; RB, residual body; B, bacteria; Pse, pseudopodia; white arrow, SARS-CoV-2 virus; black arrowhead, the site of the fusion of membrane.

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Virology Journal

ISSN: 1743-422X