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Table 1 Baseline demographic and clinical characteristics of the study cohort (n = 214)

From: Evaluation of circulating insulin-like growth factor-1, heart-type fatty acid-binding protein, and endotrophin levels as prognostic markers of COVID-19 infection severity

 

Control (n = 107)

Infected (n = 107)

P value

Gender

 Male

62

66

NS*

 Female

45

41

 

Age (years)

45.64 ± 9.411

48.84 ± 12.18

0.0162

BMI

27.91 ± 4.631

28.47 ± 4.804

NS

Hb (g/dL)

11.37 ± 1.913

11.23 ± 1.498

NS

RBCs (× 106/µL)

3.965 ± 0.4167

3.85 ± 0.4723

0.0302

WBCs (× 103/µL)

7.327 ± 4.41

3.435 ± 1.275

< 0.0001

HCT (%)

42.95 ± 8.651

34.28 ± 3.891

< 0.0001

PLT (× 103/µL)

227.1 ± 57.76

279.7 ± 81.9

< 0.0001

MCV (fL)

67.7 ± 1.987

67.75 ± 3.213

> 0.05

MCH

31.21 ± 2.163

30.55 ± 3.288

0.0419

MCHC

29.93 ± 2.408

30.94 ± 2.522

0.0017

Neutrophils

56.8 ± 6.333

68.91 ± 3.641

< 0.0001

Lymphocytes

36.72 ± 6.832

23.99 ± 4.215

 < 0.0001

Monocytes

6.449 ± 2.689

7.224 ± 2.689

0.018

NLR

1.66 ± 0.6436

2.981 ± 0.6414

< 0.0001

PLR

6.432 ± 2.282

12.01 ± 4.053

< 0.0001

Ferritin (ng/mL)

112.5 ± 34.59

230.6 ± 198.3

< 0.0001

D dimer (mg/L)

0.3005 ± 0.2099

1.232 ± 0.535

< 0.0001

Procalcitonin (pg/mL)

255.6 ± 75.92

2639 ± 2717

< 0.0001

IGF-1 (ng/mL)

47.59 ± 14.29

27.89 ± 10.62

< 0.0001

H-FABP (ng/mL)

20.09 ± 9.457

27.07 ± 16.13

< 0.0001

ETP (mg/L)

17.29 ± 4.876

17.39 ± 4.448

NS

CRP (µg/L)

5.146 ± 3.275

16.7 ± 15.35

< 0.0001

ALT (U/L)

23.35 ± 6.535

30.49 ± 6.324

< 0.0001

AST (U/L)

23.25 ± 4.55

33.14 ± 8.823

< 0.0001

Urea (mg/dL)

29.23 ± 8.388

34.77 ± 10.44

< 0.0001

LDH (U/L)

183 ± 32.42

191 ± 25.36

0.0226

ESR-1st h (mm)

11.76 ± 6.451

16.37 ± 12.45

0.0004

ESR-2nd h (mm)

25.67 ± 11.83

37.86 ± 27.66

< 0.0001

Prothrombin time (sec)

13.48 ± 1.354

16.18 ± 2.784

< 0.0001

INR

1.037 ± 0.1041

1.244 ± 0.2142

< 0.0001

O2 saturation (%)

97.66 ± 1.748

92.66 ± 4.628

< 0.0001

Consciousness

 Conscious

107 (100%)

88 (82.24%)

< 0.0001

 Unconscious

0 (0%)

19 (17.75%)

 

Smell/taste

 Yes

107 (100%)

91 (85.04%)

< 0.0001

 No

0 (0%)

16 (14.95%)

 

Smoking

 Yes

27 (25.23%)

23 (21.49%)

NS

 No

80 (74.77%)

84 (78.5%)

 

Neurological symptoms

 Yes

1 (0.934%)

106 (99.06%)

0.0352

 No

8 (7.47%)

99 (92.52%)

 
  1. HCT Hematocrit value; PLT Platelet count; MCV Mean corpuscular volume; MCH Mean corpuscular hemoglobin; MCHC Mean corpuscular hemoglobin concentration; ALT Alanine aminotransferase; AST Aspartate aminotransferase; CRP C reactive protein; ESR Erythrocyte sedimentation rate; FABP Fatty acid-binding proteins; HFABP Heart-type fatty acid binding protein; IGF-1 Insulin-like growth factor; LDH Lactate dehydrogenase; NLR Neutrophils/lymphocytes ratio; PLR Platelets/lymphocytes ratio; INR International normalized ratio
  2. *NS: Non-significant
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Virology Journal

ISSN: 1743-422X