Fig. 4
From: Pathogenicity and immunogenicity of gI/gE/TK-gene-deleted Felid herpesvirus 1 variants in cats
Protective efficacy of gI/gE- and gI/gE/TK-deleted recombinant viruses against FHV WX19 challenge in kittens. A Nasal swab samples by cats after FHV WX19 challenge. B Neutralizing antibody levels in cats after immunization and challenge. Virus-neutralizing antibodies against FHV: the reciprocal of the highest serum dilution inhibiting CPE formation in 50% of wells infected with 100 TCID50 FHV WX19. FHV-1 neutralizing antibody titers of control group (n = 4) or the recombinant virus groups (n = 4) (mean + standard deviation). Asterisks indicate statistically significant differences between the control group and the groups of three mutants: **P < 0.01